Key Benefits:
Original text
(State on 11 April 2013)
Preamble
The member States of the Council of Europe, signatories to this Convention,
Recalling that the aim of the Council of Europe is to achieve a closer union among its members and that it wishes to cooperate with other states in the protection of live animals used for experimental or other scientific purposes;
Recognising that man has a moral obligation to respect all animals and to take due account of their ability to suffer and to remember;
Recognizing, however, that man, in his quest for knowledge, health and safety, needs to use animals where it can reasonably be hoped that this will advance knowledge, or produce useful results in a way that For man or animal, in the same way as he uses animals to feed himself, to clothe himself and as a beast of money;
Determined to limit the use of animals for experimental or other scientific purposes, with the aim of replacing this use wherever possible, in particular by searching for substitution methods and Encouraging the use of alternative methods;
Wishing to adopt common provisions, in order to protect animals used in procedures liable to cause lasting damage, pain, suffering or anguish and to ensure that they, when they are unavoidable, Be kept to a minimum,
Agreed to the following:
(1) This Convention shall apply to any animal used or intended for use in any experimental procedure or other scientific procedure liable to cause lasting damage, pain, suffering or anguish. It does not apply to non-experimental agricultural or veterinary clinical practices.
2. For the purposes of this Convention:
A procedure may be carried out only for one or more of the following purposes and subject to the restrictions laid down in this Convention:
Each Party undertakes to take, as soon as possible and, in any event, within five years of the date of entry into force of this Convention in its respect, all measures necessary to give effect to the provisions of this Convention Convention and to ensure an effective system of monitoring and surveillance.
Nothing in this Convention shall affect the ability of the Parties to adopt stricter rules to ensure the protection of animals used in procedures and to control and limit the use of animals In procedures.
1. Any animal used or intended for use in a proceeding shall be provided with housing, an environment, at least some freedom of movement, food, water and care appropriate to its health and well-being. Any restriction on its ability to meet its physiological and ethological needs is limited as much as possible. For the implementation of this provision, guidance on accommodation and care of animals listed in Annex A to this Convention should be used.
2. The environmental conditions in which an animal is raised, held or used shall be subject to daily monitoring.
3. The welfare and health of the animals shall be observed with sufficient attention and frequency to prevent any lasting damage, pain, unnecessary suffering or anguish.
4. Each Party shall take the necessary measures to ensure the elimination of any deficiencies or deficiencies noted in the shortest possible time.
1. No procedure shall be carried out for any of the purposes specified in Art. 2 if it can be used reasonably and practically to another scientifically acceptable method not involving the use of an animal.
2. Each Party should encourage scientific research to develop methods that could provide the same information as that obtained in the procedures.
Where it is necessary to proceed with a procedure, the selection of the species shall be carefully examined and, if required, its reasons shall be set out to the responsible authority; when choosing between procedures, they should be selected. Use the minimum number of animals, which cause the least sustained damage, pain, suffering and anguish, and which are likely to produce the most satisfactory results.
Methods of general or local anaesthesia or analgesic methods or other methods designed to eliminate long-lasting damage, pain, suffering or anguish are applied in any procedure and during Its duration, unless:
1. Where it is intended that an animal be subject to a procedure in which it will be subject to or at risk of suffering considerable pain which may be prolonged, that procedure shall be expressly declared and justified with the responsible authority or Expressly authorized by the Commission.
2. Appropriate legislative and/or administrative measures are taken to ensure that such a procedure is not carried out unnecessarily.
Such measures include:
In the course of a proceeding, any animal used continues to fall under the provisions of s. 5, unless these provisions are inconsistent with the purpose of the procedure.
At the end of any procedure, it is decided whether the animal should be kept alive or sacrificed by a humanitarian method. An animal is not kept alive if, when even its health is returned to normal in all other respects, it is likely to continue to suffer permanent pain or anguish.
2. The decisions referred to in s. 1 of this Article shall be taken by a competent person, in particular a veterinarian or the person who, in accordance with Art. 13, is responsible for the procedure, or who has conducted it.
3. When following a procedure:
4. No animal used in a procedure that has caused severe or prolonged pain or suffering, whether or not anesthesia or analgesia has been used, may not be used in a new procedure unless the animal's condition and Well-being only returned to normal, and provided that:
Notwithstanding the other provisions of this Convention, where the legitimate purposes of the procedure so require, the responsible authority may authorise the release of the animal concerned provided that it has ensured that the maximum Possible care has been taken to safeguard the well-being of the latter. Procedures with the release of the animal are not permitted for the sole purpose of teaching or training.
A procedure for the purposes referred to in s. 2 may be carried out only by authorised persons, or under the direct responsibility of an authorised person, or if the experimental project or other scientific project concerned is authorised in accordance with the provisions of the national legislation. Such authorization shall be granted only to persons deemed competent by the responsible authority.
Livestock establishments and supplier establishments are registered with the responsible authority, subject to an exemption granted under s. 21 or 22. Such registered establishments meet the conditions set out in s. 5.
The registration provided for in Art. 14 refers to the person in charge of the institution who is competent to administer or administer the appropriate care for animals of the species raised or held in the institution.
Provisions are made in registered breeding establishments for the maintenance of a register in which all the animals are registered, and the number and species of animals exiting the establishment, the date Of their output and the name and address of the recipient.
2. Arrangements shall be made in the registered supplier establishments for the maintenance of a register in which the number and species of animals arriving in and out of the establishment are indicated, the dates of the movements effected, The supplier of the animals concerned, and the name and address of the consignee.
The responsible authority shall prescribe the nature of the records to be kept and made available to it by the person in charge of the establishments referred to in s. 1 and 2 of this article. These records shall be kept for a minimum period of three years from the date of the last entry.
In any establishment, each dog and cat, before weaning, is the subject of an individual and permanent marking, carried out in the least painful manner possible.
2. When an unmarked dog or cat enters an establishment for the first time after weaning, it is marked as soon as possible.
3. When a dog or a non-weaned cat and it has not been possible to mark beforehand is transferred from one institution to another, a registration document containing complete information, specifying in particular the identity of its mother, is Held until its marking.
4. The characteristics of the identity and origin of each dog or cat shall appear on the registers of the establishment.
The user institutions are registered with or otherwise approved by the responsible authority and satisfy the requirements set out in s. 5.
Provisions are made to ensure that user establishments have facilities and equipment adapted to the animal species and procedures used, and that their design, construction and mode of operation allow Ensure that procedures are carried out as efficiently as possible, with the aim of achieving consistent results with as few animals as possible and the minimum of lasting damage, pain, suffering or anguish.
In user institutions:
1. The animals of the species listed below that are intended for use in procedures are acquired directly from registered establishments or come from such establishments, unless a general or special exemption Has been obtained in accordance with the provisions to be made by the Party:
Mouse |
Mus musculus |
Rabbit |
Oryctolagus cuniculus |
Rat |
Rattus norvegicus |
Chien |
Canis familiaris |
Cobaye |
Cavia porcellus |
Chat |
Felis catus |
Golden Hamster |
Mesocricetus auratus |
Quail |
Coturnix coturnix |
2. Each Party undertakes to extend the provisions of paragraph 1 of this article to other species, in particular the order of primates, where a reasonable prospect of having sufficient supply of animals of the Species concerned and raised for this purpose.
3. Wandering animals of domestic species are not used in procedures. The general exemption provided for in s. 1 of this article cannot be extended to stray dogs and cats.
In user establishments, only animals from registered breeding establishments or registered supplier establishments are used, unless a general or special exemption has been obtained in accordance with the Provisions to be made by the Party.
Where authorized by the responsible authority, procedures may be conducted outside the user's premises.
Arrangements shall be made for the records to be kept and submitted to the users of the registers at any request of the responsible authority. These records meet the requirements of s. 27 and also indicate for all animals acquired the number, species, supplier and date of arrival.
1. Procedures for teaching, training or retraining for the performance of a profession or other activities, including the care of animals used or intended for use, shall be notified to the responsible authority and Carried out by or under the supervision of a competent person, who is responsible for ensuring that the procedures are in conformity with national law within the meaning of this Convention.
2. The procedures envisaged for teaching, training or retraining for purposes other than those mentioned in par. 1 above are not allowed.
3. The procedures referred to in paragraph 1 of this Article shall be limited to those strictly necessary for the purposes of the education or training concerned and shall be permitted only if their objective cannot be achieved by means of methods Audiovisual of comparable value or by any other appropriate means.
Persons performing procedures or taking part, as well as persons providing care to animals used in procedures, including control, must have received appropriate education and training.
Each Party shall collect statistical data on the use of animals in proceedings; such data shall be communicated to the public where such communication is lawful.
2. Data are collected for:
Subject to the provisions of national law on confidentiality and confidentiality, each Party shall submit to the Secretary General of the Council of Europe data on the matters referred to in subs. 2 of the art. 27, presented in the form provided for in Annex B to the Convention.
2. The Secretary General of the Council of Europe shall publish the statistical information received from the Parties with regard to the points mentioned in para. 2 of the art. 27.
Each Party shall be invited to communicate to the Secretary General of the Council of Europe the address of its national authority to which information on more complete national statistics may be obtained upon request.
These addresses will be included in the statistical publications established by the Secretary General of the Council of Europe.
1. In order to avoid unnecessary duplication of procedures required by health and safety legislation, each Party shall recognize, where possible, the results of proceedings in the territory of another Party.
To this end, the Parties undertake to provide mutual assistance, in particular by providing information on their right and administrative practice concerning the requirements of the procedures required to support applications Registration of products, as well as factual information concerning the procedures carried out in their territory and the authorisations or other administrative details relating to such procedures.
The Parties shall, within five years after the entry into force of this Convention and thereafter every five years, or more often if the majority of the Parties so request, undertake multilateral consultations within the Council of Europe, With a view to examining the application of this Convention, as well as the desirability of its revision or enlargement of some of its provisions. These consultations shall take place at meetings convened by the Secretary General of the Council of Europe. The Parties shall communicate to the Secretary General of the Council of Europe, at least two months before the meeting, the name of their representative.
This Convention shall be open for signature by the member States of the Council of Europe and of the European Communities. It will be subject to ratification, acceptance or approval. Instruments of ratification, acceptance or approval shall be deposited with the Secretary General of the Council of Europe.
This Convention shall enter into force on the first day of the month following the expiration of a period of six months after the date on which four member States of the Council of Europe have expressed their consent to be bound by the Convention Pursuant to the provisions of s. 31.
(2) For any Signatory who subsequently expresses its consent to be bound by the Convention, it shall enter into force on the first day of the month following the expiration of six months after the date of deposit of the instrument of ratification, Acceptance or approval.
After the entry into force of this Convention, the Committee of Ministers of the Council of Europe may invite any State which is not a member of the Council to accede to this Convention by a decision taken by a majority provided for in Art. 20.d of the Statute of the Council of Europe 1 And unanimously by the representatives of the Contracting States having the right to sit on the Committee.
2. For any acceding State, the Convention shall enter into force on the first day of the month following the expiration of a period of six months after the date of the deposit of the instrument of accession with the Secretary General of the Council of Europe.
(1) Any Signatory may, at the time of signature or at the time of deposit of its instrument of ratification, acceptance, approval or accession, formulate one or more reservations; however, no reservation may be made concerning art. 1 to 14 and 18 to 20.
2. Any Party which has made a reservation under the preceding paragraph may withdraw it in whole or in part by sending a notification to the Secretary General of the Council of Europe. The withdrawal shall take effect on the date of receipt of the notification by the Secretary General.
(3) The Party which has made a reservation concerning a provision of this Convention shall not be entitled to the application of that provision by another Party; however, it may, if the reservation is partial or conditional, claim to The application of this provision to the extent that it has accepted it.
(1) Any Signatory may, at the time of signature or at the time of deposit of its instrument of ratification, acceptance, approval or accession, designate the territory or territories to which this Convention shall apply.
(2) Any Party may, at any time thereafter, by a declaration addressed to the Secretary General of the Council of Europe, extend the application of this Convention to any other territory designated in the declaration. The Convention shall enter into force in respect of that territory on the first day of the month following the expiration of a period of six months after the date of receipt of the declaration by the Secretary General.
(3) Any declaration made under the two preceding paragraphs may be withdrawn, in respect of any territory designated in that declaration, by notification addressed to the Secretary General. The withdrawal shall take effect on the first day of the month following the expiration of a period of six months after the date of receipt of the notification by the Secretary General.
1. Any Party may, at any time, denounce this Convention by sending a notification to the Secretary General of the Council of Europe.
(2) Denunciation shall take effect on the first day of the month following the expiration of a period of six months after the date of receipt of the notification by the Secretary General.
The Secretary General of the Council of Europe shall notify the member states of the Council of Europe, the European Communities and any State which has acceded to this Convention:
In witness whereof, The undersigned, duly authorized to that effect, have signed this Convention.
Done at Strasbourg, on 18 March 1986, in English and in French, both texts being equally authentic, in a single copy which shall be deposited in the archives of the Council of Europe. The Secretary General of the Council of Europe shall transmit certified copies to each member state of the Council of Europe and to the European Communities, and to any State invited to accede to this Convention.
(Suivent signatures)
(art. 5 of the Convention)
1. The member states of the Council of Europe have decided that they propose to protect live animals used for experimental and other scientific purposes, to ensure that lasting damage, pain, suffering or The anguish they suffer as consequences of procedures on them are limited to the bare minimum.
2. It is true that certain procedures are carried out on the ground with wild animals living in freedom and providing for their own subsistence, but they are, however, very limited. The vast majority of animals used in the proceedings must, for practical reasons, be maintained under any physical control in facilities ranging from outside the park to small animal cages in a pet shop. Laboratory. In this situation, many interests are in conflict. On the one hand there is the animal, whose needs for movement, social relations and other manifestations of life must be restricted, on the other hand, the experimenter and its assistants, which require full control of the animal and its environment. In this conflict of interest, it can sometimes only be of secondary interest to the animal.
3. Therefore, the European Convention on the Protection of Vertebrate Animals used for experimental or other scientific purposes provides in its art. " Any animal used or intended for use in a proceeding shall benefit from housing, an environment, at least a certain freedom of movement, food, water and care appropriate to its health and well-being. Any restriction on its ability to meet its physiological and ethological needs is limited as much as possible."
4. This appendix contains a number of guidelines based on current knowledge and practice related to accommodation and animal care. It explains and supplements the basic principles adopted in art. 5. The aim is to help the authorities, institutions and individuals in their pursuit of the objectives of the Council of Europe.
5. The word "care", used in relation to animals used or intended for use in procedures, covers all aspects of the relationship between the animal and man. It covers all material and other resources mobilized by man to obtain and maintain an animal in a physical and mental state where it suffers as little as possible and bears the best support for procedures. Care must be taken from the time the animal is chosen for use in proceedings until the animal is sacrificed by a humanitarian method or otherwise by the establishment at the end of the procedure, in accordance with the Provisions of s. 11 of the Convention.
6. The purpose of the Annex is to provide advice on the structure of premises for animals. However, there are several methods of rearing and maintaining laboratory animals that differ primarily in the degree of control of the microbiological environment. It must be kept in mind that the staff concerned will sometimes have to be able to judge the character and conditions of the animals when the recommended standards of space may be insufficient, for example with animals Particularly aggressive. The application of the guidelines in this Annex should take into account the requirements of these different situations. In addition, the status of these guidelines should be clarified. Unlike the provisions of the Convention, they are not binding: they are discretionary recommendations intended to serve as a guide to practices and standards to which all concerned Should make a conscious effort to achieve this. It is for this reason that the word "devrai (en) t" had to be used throughout the text, even when the word "must (must)" seemed more appropriate. It is obvious, for example, that food and water Must Be provided (see 3.7.2 and 3.8).
Finally, for practical and financial reasons, existing animal facilities should not be replaced as long as they are in good condition or have not become unnecessary in any other way. Pending replacement by installations that comply with the suggested guidelines, they should be observed as far as possible by adapting the number and size of the animals to the existing cages and enclosures.
For the purposes of Schedule A, in addition to the definitions contained in s. 1.2 of the Convention:
1.1. Functions and General Design
1.1.1. Every facility should be designed to provide an appropriate environment for the species in the facility. It should also be designed to prevent unauthorized access.
Facilities that are integrated into a larger building should also be protected by adequate construction standards and provisions limiting the number of entrances and preventing the movement of unauthorized persons.
1.1.2. It is recommended that a facility maintenance program be used to prevent equipment failure.
1.2. Accommodation Premises
1.2.1. All necessary measures should be taken to ensure the prompt and effective cleaning of premises and the maintenance of adequate hygiene standards. The ceilings and walls should be resistant and provide a smooth, waterproof and easily washable surface. Particular attention should be paid to the joints of doors, pipes, pipes and cables. The doors and, where appropriate, windows should also be constructed or protected in such a way as to prevent access to undesirable animals. If necessary, an oculus can be arranged in the door. The floor should be smooth, impermeable, with a non-slippery surface and easy to wash, capable of withstanding the weight of lockers and other heavy installations without damage. Where escape vents exist, they should be properly covered and equipped with a grid to prevent the penetration of animals.
1.2.2. Premises where animals can move freely should have walls and floors covered with a coating that is particularly resistant to bear the significant wear and tear caused by the animals and the cleaning. This coating should not be harmful to the health of animals and designed to prevent injury. Evacuation balls are desirable on such premises. Additional protection should be provided for equipment or facilities so that they cannot be damaged by animals or harm the animals themselves. If there are external enclosures, the necessary measures should be taken, if necessary, to prevent public and animal access.
1.2.3. Premises for farm animals (cattle, sheep, goats, pigs, horses, poultry, etc.) should at least comply with the standards set out in the European Convention on the Protection of Animals in Farming 1 And by the national veterinary and other authorities.
1.2.4. The majority of animal facilities are usually designed to house rodents. Very often these premises can also be used to house larger species. Care should be taken not to cohabit incompatible species.
1.2.5. Premises where animals are housed should be equipped with facilities, where appropriate, for the implementation of minor procedures and handling.
1.3. Laboratories and general and special procedure rooms
1.3.1. In livestock establishments or suppliers, appropriate facilities for the preparation of shipments of animals ready for shipment should be available.
1.3.2. All establishments should also have at least laboratory facilities to establish simple diagnoses, conduct examinations Post-mortem, And/or collect samples for further laboratory tests that will be carried out elsewhere.
1.3.3. Provisions should be made for the reception of animals in such a way that they, upon their arrival, do not endanger the animals already present in the facility, for example by quarantine. General and special procedural rooms should be available for cases where procedures or observations are not desirable in the room where the animals are housed.
1.3.4. Appropriate facilities should be available to allow sick or injured animals to be housed separately.
1.3.5. Where appropriate, it would also be appropriate to have one or more separate operating rooms, equipped in such a way as to permit surgical procedures under aseptic conditions. Premises should be available to allow the animals to recover after an operation when necessary.
1.4. Service Premises
1.4.1. The premises used to store food should be fresh, dry, protected from vermin and insects, and those used for bedding should be dry and protected from vermin and insects. Other materials that could be contaminated or could present a risk should be kept separate.
1.4.2. Premises should be available for storage of clean cages, instruments and other equipment.
1.4.3. The cleaning and washing facilities should be spacious enough to contain the equipment necessary for decontamination and cleaning of the equipment used. The cleaning circuit should be arranged in such a way as to separate the passage from clean and dirty equipment in order to avoid contamination of the equipment that has just been cleaned. The walls and floor should be covered with an appropriate resistance and the ventilation system powerful enough to remove excessive heat and humidity.
1.4.4. Provision should be made for storage in satisfactory hygiene conditions and for the disposal of carcasses and animal waste. If on-site incineration is not possible or desirable, appropriate arrangements should be made for the disposal of these substances in accordance with local regulations and orders. Special precautions should be taken with highly toxic or radioactive waste.
1.4.5. The design and construction of traffic areas should be consistent with animal housing standards. Corridors should be wide enough to allow easy movement of rolling stock.
2.1. Breakdown
2.1.1. The accommodation facilities of the animals should have a ventilation system appropriate to the requirements of the hosted species. The purpose of the ventilation system is to provide clean air and reduce odours, toxic gases, dust and infection agents of any kind. Another objective is to contribute to the elimination of excessive heat and humidity.
2.1.2. Air on the premises should be renewed frequently. A ventilation rate of 15 to 20 air renewals per hour is generally sufficient. However, in some circumstances, when stand density is low, a ventilation rate of 8 to 10 air renewals per hour may be sufficient and mechanical ventilation may even be unnecessary. In other cases, it may be necessary to have more frequent renewal. Untreated air recirculation should in any case be avoided. It should be noted, however, that even the most effective system cannot compensate for poor cleaning habits or neglect.
2.1.3. Ventilation systems should be designed to avoid harmful air currents.
2.1.4. Smoking should be prohibited in the premises in which animals are found.
2.2. Temperature
2.2.1. Table 1 shows the range in which it is recommended to maintain temperature. It should also be noted that the figures apply only to adult and normal animals. Newborns and young people often need a much higher temperature. The temperature setting of the premises should take into account any changes in the thermoregulation of the animals due to particular physiological conditions or the effects of the procedures.
2.2.2. In the climatic conditions prevailing in Europe, it may be necessary to provide for a ventilation system with devices for both heating and cooling air.
2.2.3. In user establishments, the temperature of the accommodation spaces of the animals should be strictly controlled. Indeed, ambient temperature is a physical factor that has a significant effect on the metabolism of all animals.
2.3. Humidity
Extreme variations in relative humidity (RH) have an adverse effect on the health and welfare of animals. It is therefore recommended that the level of HR at the premises be appropriate for the hosted species and would normally be maintained at 55 % +/ - 10 %. Values below 40 % or above 70 % should be avoided for an extended period of time.
2.4. Lighting
In rooms without windows, it is necessary to provide controlled artificial lighting for, at the same time, to satisfy the biological requirements of animals and to provide a satisfactory working environment. It is also necessary to exercise control of the light intensity and the light-dark cycle. When albino animals are raised, their sensitivity to light should be taken into account (see also 2.6).
2.5. Noise
Noise can be an important factor in the disturbance of animal facilities. Accommodation and procedural rooms should be isolated from sources of high noise in the range of audible sounds and high frequency sounds, in order to avoid disturbance of animal behaviour and physiology. Sudden noise may result in considerable changes in organic functions but, since some noises are often unavoidable, it may be appropriate in certain circumstances to provide accommodation and Experimental rooms with a continuous sound background, of moderate intensity, such as soft music.
2.6. Alarm System
An installation housing a large number of animals is vulnerable. It is therefore recommended that facilities be properly protected by providing systems to detect fires and the entry of unauthorized persons. Technical defects or breakdowns of the ventilation system constitute another hazard which may lead to disturbance and even death of animals by suffocation or excess heat or, in the least serious cases, which may have on a procedure Negative effects to the point of making it fail and to force it to be redone. Appropriate monitoring devices should therefore be installed in connection with the heating and ventilation system to allow staff to monitor their operation in general. Where appropriate, it would be desirable to install an emergency generator to ensure the operation of animal survival and lighting equipment in the event of a failure or interruption in the supply of electricity. Clear instructions for emergency arrangements should be prominently displayed. It is recommended that an alarm system be provided in fish pens in the event of a failure of the water supply. It should be ensured that the functioning of the alarm system disrupts animals as little as possible.
3.1. Health
3.1.1. The person in charge of the establishment should ensure that a regular inspection of the animals and a control of the conditions in which they are housed and treated are carried out by a veterinarian or other competent person.
3.1.2. Due to the potential risk to animals, the health and hygiene of personnel should be given special attention.
3.2. Capturing
Wild animals and animals from stray animals should be captured only by humanitarian methods and by experienced people who have a thorough knowledge of the habits and habitats of the animals to be captured. If an anesthetic or any medication is to be used in the capture operation, it should be administered by a veterinarian or other competent person. Any severely injured animal should be presented as soon as possible to a veterinarian for treatment. If, in the opinion of the veterinarian, the animal can only survive with suffering and pain, it should be immediately sacrificed by a humanitarian method. In the absence of a veterinarian, any seriously injured animal should be immediately sacrificed by a humanitarian method.
3.3. Packaging and transport conditions
There is no doubt that transportation is a difficult test for animals that should be mitigated to the extent possible. Animals should be in good health to be transported and the consignor has a duty to control that they are transported. Animals ill or in poor condition should never be transported, except for therapeutic or diagnostic purposes. Special care should be given to pregnant females in the advanced gestational condition. Females at risk of calving off the road, or those that have calving during the previous forty-eight hours, and their offspring, should not be transported. Shipper and carrier should take all necessary precautions during packaging, loading and transit, in order to avoid unnecessary suffering caused by inadequate ventilation, exposure to temperatures Extreme, lack of food and water, long delays, etc. The consignee should be properly informed of the details of transport and the characteristics of the transport documents in order to ensure prompt handling and delivery to the place of destination. Even in the case of States not party to the European Convention on the Protection of Animals in International Transport 2 , it is recommended that the provisions of the Act be strictly adhered to. It is also recommended that strict compliance with national laws and regulations, as well as live animal regulations of the International Air Transport Association and the Air Transport Association of Animals (Animal Air Transport Associ A (a) .
3.4 . Receipt and Unpacking
Packages containing animals should be recovered and unpacked without undue delay. After inspection, animals should be transferred to clean cages or pens where they will be given food and water in an appropriate manner. Animals ill or in poor physical condition should be observed and kept away from other animals. They should be reviewed as soon as possible by a veterinarian or other competent person and treated as appropriate. Animals with no chance of recovery should be immediately sacrificed by a humanitarian method. Finally, all animals received must be registered and marked in accordance with the provisions of Art. 16, 17 and 24 of the Convention. Boxes used for transportation should be destroyed immediately if decontamination facilities are not available.
3.5 Quarantine, isolation and acclimatization
3.5.1. The goals of the quarantine are:
Unless the health status of the animals entering an establishment is satisfactory, it is recommended that they be quarantined. In certain cases, such as rabies, the duration may be fixed by the national law of the Party. In other cases, it will be variable and should be determined according to the circumstances by a competent person, normally the veterinarian hired by the institution (see also Table 2).
Animals may be used for procedures during the quarantine period as long as they have acclimatized to their new environment and do not pose any significant risk to other animals or to humans.
3.5.2. It is recommended that premises be provided to isolate animals that show signs of ill health or that are suspected of being in poor health and that could pose risks to humans or other animals.
3.5.3. Even if the animals are found to be in good health, it is good zootechnical practice to have them undergo a period of acclimation before using them in a procedure. The time required depends on several factors, such as the stress experienced by the animal, which is itself a function of several factors, such as the duration of transport and the age of the animal. The duration of this period shall be decided by the competent person.
3.6 . Cage
3.6.1. Two large systems can be distinguished for the accommodation of animals. The first is the existing system in livestock establishments, suppliers and users of the bio-medical sector and intended for the accommodation of animals, such as rodents, rabbits, carnivores, birds and primates, not Humans, sometimes also ruminants, pigs and horses. Suggested guidelines for cages, paddocks (boxes), outdoor enclosures, and stalls suitable for these facilities are shown in Tables 3 to 13. Additional information on the minimum floor space of the cages can be found in diagrams 1 through 7. In addition, corresponding indications for the evaluation of the stocking density in cages are shown in diagrams 8 to 12.
Second, it is the system that often exists in establishments engaged in procedures only with farm animals or similar sized animals. The means available in such establishments should not be lower than those advocated by common veterinary standards.
3.6.2. Cages and enclosures should not be made in material that is harmful to the health of animals; they should be designed to prevent injury to animals and, unless disposable, to be constructed in a material Resistant to cleaning and decontamination techniques. Special attention should be given to the design of cage and enclosure floors, which should vary according to the species and age of the animal and be designed to facilitate the disposal of the droppings.
3.6.3. Outer enclosures should be designed for species well-being. They should allow for the satisfaction of certain ethological needs (for example, the possibility of climbing, isolating or temporarily sheltering). They should also allow for effective cleaning and avoid contact with other animals.
3.7. Feeding
3.7.1. In the choice, production and preparation of food, precautions should be taken to avoid chemical, physical and microbiological contamination. They should be packed, where appropriate, in sealed sealed bags bearing the date of manufacture. Packaging, transport and storage should be designed to avoid contamination, deterioration or destruction. Storage facilities should be cool, dark, dry, protected from vermin and insects. Perishable foods such as green fodder, vegetables, fruits, meat, fish, etc., should be stored in cold rooms, refrigerators or freezers.
All hoppers, troughs or other utensils used to feed the animals should be cleaned and, if necessary, sterilized regularly. If wet foods are used or foods are easily contaminated with water, urine, etc., daily cleaning is required.
3.7.2. The presentation of food varies depending on the species, but it should be such that it meets the physiological needs of the animal. In addition, the necessary arrangements should be made for each animal to have access to food.
3.8. Water
3.8.1. All animals must have permanently uncontaminated drinking water. During transport, it is recognized that water is supplied as part of a wet diet. However, water is a vehicle of micro-organisms, and that is why it should be provided in such a way that the risks are minimized. Two methods are commonly used, baby bottles and automatic watering systems.
3.8.2. For small animals such as rodents and rabbits, bottles are often used. When such containers are used, they should be made of a translucent material in order to control the contents. The neck should be large enough to allow for easy and effective cleaning, and if the bottle is made of plastic, it should be non-leachable. Capsules, caps and hoses should also be able to be sterilized and easy to clean. All bottles and accessories should be dismantled, cleaned and sterilized at appropriate and regular intervals. It would be preferable to replace the baby bottles with clean and sterilized bottles each time, rather than refilling them in the animal accommodation facility.
3.8.3. Automatic troughs should be regularly checked and maintained, and operation should be regularly monitored to prevent accidents and the development of infections. If compact floor cages are used, care should be taken to minimize the risk of flooding. It is also recommended that a bacteriological examination of the system be carried out regularly to control water quality.
3.8.4. Water from the public network contains a few micro-organisms that are generally considered safe, unless we work with microbiologically defined animals. In such cases, water should be treated. The water in the public supply system is generally chlorinated to limit the development of micro-organisms. This chlorination is not always sufficient to limit the growth of some potential pathogens, such as pseudomonads. An additional precaution may be to increase chlorine levels in the water or acidify the water to achieve the desired effect.
3.8.5. Fish, amphibians and reptiles have a highly variable species tolerance of acidity, chlorine and other chemicals. Therefore, provisions should be made to adapt the water supply of aquariums and viviers to the needs and tolerances of individual species.
3.9. Litigation
Litters should be dry, absorbent, dust-free, non-toxic, free of any infection or vermin agent or any other form of contamination. In particular, the use of sawdust or litter materials derived from chemically treated wood should be avoided. Some industrial by-products or wastes (such as shredded paper) may also be used.
3.10. Exercise and handling
3.10.1. Every opportunity should be taken to allow the animals to exercise.
3.10.2. The behaviour of the animal during a procedure depends very much on its trust in man, confidence that must be developed. The wild or wandering animal will probably never be the ideal animal for experiments. This is not the case with the domestic animal born and raised in contact with the man. Trust once established, however, should be preserved. It is therefore recommended that frequent contact be maintained so that animals become familiar with the presence and activity of humans. If so, we would have to spend some time talking to animals, dealing with them and cleaning them up. Staff should be benevolent, gentle and firm when dealing with animals.
3.11. Cleaning
3.11.1. The quality of an animal facility depends very much on its good hygiene. Clear instructions should be given for the renewal of litter, in cages and pens.
3.11.2. Adequate rules should be established for cleaning, washing, decontamination and, if necessary, the sterilization of cages and accessories, baby bottles and the rest of the equipment. It would also be appropriate to maintain a high level of cleanliness and order in the premises reserved for animals as well as in the washing and storage facilities.
3.11.3. Regular cleaning and replacement, where appropriate, of materials covering the soil in cages, enclosures and outdoor enclosures should be used to prevent them from becoming a source of infection and infestation by Parasites.
3.12. Humanitarian sacrifice of animals
3.12.1. Any humanitarian method of sacrifice of animals requires knowledge which can only be acquired through appropriate training.
3.12.2. A deeply unconscious animal can be bled, but drugs that paralyze muscles before the loss of consciousness, those with the effects of curare, and electrocution without the passage of current through the brain, should not be Used without prior anesthesia.
The removal of the body should not occur before the appearance of the corpse rigidity.
(guidelines for accommodation and care of animals)
Table 1
Guidelines for Local Temperature
(animals housed in cages or interlocks)
Species or groups of species |
Optimal range in ° C |
New Non-Human World Primates |
20-28 |
Mouse |
20-24 |
Rat |
20-24 |
Syrian Hamster |
20-24 |
Gerbille |
20-24 |
Cobaye |
20-24 |
Primates of the Old Non-Human World |
20-24 |
Quail |
20-24 |
Rabbit |
15-21 |
Chat |
15-21 |
Chien |
15-21 |
Furet |
15-21 |
Poultry |
15-21 |
Pigeon |
15-21 |
Pork |
10-24 |
Goat |
10-24 |
Sheep |
10-24 |
Bovine |
10-24 |
Horse |
10-24 |
Note: In special cases, for example, when animals are very young or have no hairs, warmer accommodation temperatures than indicated may be required.
Table 2
Guidelines for Local Quarantine Periods
Keynote note: For imported animals, all quarantine periods should be based on the Parties' national regulations. For local quarantine periods, the period should be determined in the circumstances by a competent person, normally by a veterinarian appointed by the institution.
Species |
Days |
Mouse |
5-15 |
Rat |
5-15 |
Gerbille |
5-15 |
Cobaye |
5-15 |
Syrian Hamster |
5-15 |
Rabbit |
20-30 |
Chat |
20-30 |
Chien |
20-30 |
Non-human Primates |
40-60 |
Table 3
Guidelines for the Caging of Small Rodents and Rabbits
(storage and procedures)
Species |
Minimum Floor Area of the Cage 2 |
Minimum height of the cage cm |
|
Mouse |
180 |
12 |
|
Rat |
350 |
14 |
|
Syrian Hamster |
180 |
12 |
|
Cobaye |
600 |
18 |
|
Rabbit |
1 kg |
1400 |
30 |
2 kg |
2000 |
30 |
|
3 kg |
2500 |
35 |
|
4 kg |
3000 |
40 |
|
5 kg |
3600 |
40 |
|
Note: The "cage height" refers to the vertical distance between the ground of the cage and the top horizontal part of the lid or cage.
In planning procedures, the potential growth of animals should be taken into account in order to ensure adequate space in accordance with this table during all phases of the procedures.
See also diagrams 1 through 5 and 8 to 12.
Table 4
Guidelines for the Caging of Small Rodent Rodents
Species |
Minimum ground surface of the cage for a mother and its range 2 |
Minimum height of the cage cm |
Mouse |
200 |
12 |
Rat |
800 |
14 |
Syrian Hamster |
650 |
12 |
Cobaye |
1200 |
18 |
Cobaye in harems |
1000 per adult |
18 |
Note: For the definition of "cage height", see the note in Table 3.
Table 5
Guidelines for the Cenning of Reproductive Rabbits
Weight of the lapin kg |
Minimum ground surface of the cage for a rabbit and its range m 2 |
Minimum cage height Cm |
Minimum nest area m 2 |
1 |
0.30 |
30 |
0.10 |
2 |
0.35 |
30 |
0.10 |
3 |
0.40 |
35 |
0.12 |
4 |
0.45 |
40 |
0.12 |
5 |
0.50 |
40 |
0.14 |
Note: For the definition of "cage height", see the note in Table 3.
The minimum ground surface of the cage for a rabbit and its range includes the ground surface of the nest box.
See also diagram 6.
Table 6
Guidelines for the accommodation of cats
(procedures and reproduction)
Cat Weight kg |
Minimum floor area of the cage by cat m 2 |
Minimum height of the cage cm |
Minimum ground surface of the cage by cat and range m 2 |
Minimum soil surface of the enclosure by cat and range m 2 |
0.5-1 |
0.2 |
50 |
- |
- |
1-3 |
0.3 |
50 |
0.58 |
2 |
3-4 |
0.4 |
50 |
0.58 |
2 |
4-5 |
0.6 |
50 |
0.58 |
2 |
Note: The accommodation of cats in cages should be strictly limited. Confined cats should be able to exercise at least once a day when this does not interfere with procedures. Cat pens should always be equipped with excreta trays, a rest area and objects to climb and claw.
"Cage height" means the vertical distance between the highest point of the ground of the cage and the lowest point of the top of the cage.
For the calculation of the minimum soil surface, the surface of the rest trays may be included. The minimum floor space for a cat and its range includes the 0.18 m 2 area of the kittens box.
See also diagram 7.
Table 7
Guidelines for the accommodation of dog in cages
(procedures)
Height of the dog with shoulder height |
Minimum ground surface of the cage per dog m 2 |
Minimum height of the cage cm |
30 |
0.75 |
60 |
40 |
1.00 |
80 |
70 |
1.75 |
140 |
Note: Dogs should not be stored in cages for longer than is absolutely necessary for the purposes of the procedure. Cage dogs should be able to exercise at least once a day, unless this is inconsistent with the purpose of the procedure. A time limit should be set beyond which an animal should not be confined without daily exercise. Exercise surfaces should be large enough to allow animals to move freely. Grilled soil should be used in dog cages only if required by the procedure.
In view of the large differences in size and the limited relationship between the size and weight of the different breeds of dogs, the height of the cage should be fixed according to the height of the body of each animal measured at the shoulders. As a general rule, the minimum height of the cage should be twice its height measured at the shoulders.
For the definition of "cage height", see the notes in Table 6.
Table 8
Guidelines for the accommodation of dogs in enclosures
(storage, procedures and reproduction)
Weight of the dog kg |
Minimum soil surface of the enclosure by dog m 2 |
Adjacent surface of minimal exercise per dog |
||
Kg |
M 2 |
Up to 3 dogs m 2 |
More than 3 dogs m 2 |
|
< |
6 |
0.5 |
0.5 (1, 0) |
0.5 (1, 0) |
6- |
10 |
0.7 |
1.4 (2, 1) |
1.2 (1, 9) |
10- |
20 |
1.2 |
1.6 (2, 8) |
1.4 (2, 6) |
20- |
30 |
1.7 |
1.9 (3, 6) |
1.6 (3, 3) |
> |
30 |
2.0 |
2.0 (4, 0) |
1.8 (3, 8) |
Note: The figures in brackets indicate the total area per dog, i.e. the ground surface of the enclosure plus the adjacent area of exercise. Dogs kept permanently in outdoor enclosures should have access to a sheltered location to protect themselves from adverse weather conditions. When dogs are housed on grilled surfaces, a full surface should be provided to sleep. Grilled soil should be used only if required by the procedure. Separations between enclosures should be made in such a way that the dogs cannot injure each other.
All pens should have an appropriate flow system.
Table 9
Guidelines for the Caging of Non-Human Primates
(storage, procedures and reproduction)
Keynote note: Given the very wide variety of sizes and characteristics of primates, it is particularly important to reconcile the size, interior equipment and size of the cages with their specific needs. The total volume of the cage is just as important for primates as the minimum ground surface. In general, the height of the cage, at least for anthropoid and other simian monkeys, should be its largest dimension. At a minimum, the cages should be high enough to allow the animals to stand. The minimum height of the cage for the brachiers should allow these animals to swing in the middle of the ceiling and without their feet touching the floor of the cage. Where appropriate, perches should be installed to allow the animals to use the upper part of the cage.
It is possible to house two primate primates in a cage. When primates cannot be accommodated in two, cages should be positioned so that primates can be seen, but, if so, it should also be possible to prevent them from seeing themselves.
Subject to these observations, the following table provides a general guideline for the caging of the most commonly used species groups (superfamilies of ceboids and cercopaecidae).
Weight of primate kg |
Minimum ground surface of the cage for one or two animals m 2 |
Minimum height of the cage cm |
|
< |
1 |
0.25 |
60 |
1- |
3 |
0.35 |
75 |
3- |
5 |
0.50 |
80 |
5- |
7 |
0.70 |
85 |
7- |
9 |
0.90 |
90 |
9- |
15 |
1.10 |
125 |
15- |
25 |
1.50 |
125 |
Note: For the definition of "cage height", see the note in Table 6.
Table 10
Guidelines for Hog Cage
(storage and procedures)
Pork Weight kg |
Minimum ground surface of the cage per pig m 2 |
Minimum height of the cage cm |
5-15 |
0.35 |
50 |
15-25 |
0.55 |
60 |
25-40 |
0.80 |
80 |
Note: This table would also apply to piglets. Pigs should not be kept in cages unless absolutely necessary for the purpose of the procedure and, in this case, only for a minimum period of time.
For the definition of "cage height", see the note in Table 6.
Table 11
Guidelines for the accommodation of farm animals in enclosures
(storage and procedures in user institutions)
Species and weight kg |
Minimum soil surface of the enclosure m 2 |
Minimum enclosure length m |
Minimum height of separation between enclosure m |
Minimum soil surface of the enclosure for groups m 2 /animal |
Minimum height of feeder per head m |
|
Swine |
||||||
10- |
30 |
2 |
1.6 |
0.8 |
0.2 |
0.20 |
30- |
50 |
2 |
1.8 |
1.0 |
0.3 |
0.25 |
50- |
100 |
3 |
2.1 |
1.2 |
0.8 |
0.30 |
100- |
150 |
5 |
2.5 |
1.4 |
1.2 |
0.35 |
> |
150 |
5 |
2.5 |
1.4 |
2.5 |
0.40 |
Sheep |
||||||
< |
70 |
1.4 |
1.8 |
1.2 |
0.7 |
0.35 |
Goats |
||||||
< |
70 |
1.6 |
1.8 |
2.0 |
0.8 |
0.35 |
Cattle |
||||||
< |
60 |
2.0 |
1.1 |
1.0 |
0.8 |
0.30 |
60- |
100 |
2.2 |
1.8 |
1.0 |
1.0 |
0.30 |
100- |
150 |
2.4 |
1.8 |
1.0 |
1.2 |
0.35 |
150- |
200 |
2.5 |
2.0 |
1.2 |
1.4 |
0.40 |
200- |
400 |
2.6 |
2.2 |
1.4 |
1.6 |
0.55 |
> |
400 |
2.8 |
2.2 |
1.4 |
1.8 |
0.65 |
Adult Horses |
13.5 |
4.5 |
1.8 |
- |
||
Table 12
Guidelines for the accommodation of farm animals in stalls
(storage and procedures in user institutions)
Species and weight kg |
Minimum stall m surface 2 |
Minimum Length of the m stall |
Minimum height of separation between the m stalls |
|
Swine |
||||
100- |
150 |
1.2 |
2.0 |
0.9 |
> |
150 |
2.5 |
2.5 |
1.4 |
Sheep |
||||
< |
70 |
0.7 |
1.0 |
0.9 |
Goats |
||||
< |
70 |
0.8 |
1.0 |
0.9 |
Cattle |
||||
60- |
100 |
0.6 |
1.0 |
0.9 |
100- |
150 |
0.9 |
1.4 |
0.9 |
150- |
200 |
1.2 |
1.6 |
1.4 |
200- |
350 |
1.8 |
1.8 |
1.4 |
350- |
500 |
2.1 |
1.9 |
1.4 |
> |
500 |
2.6 |
2.2 |
1.4 |
Adult Horses |
4.0 |
2.5 |
1.6 |
|
Note: The stalls should be broad enough to allow the animals to grow comfortably.
Table 13
Guidelines for Bird Cenning
(storage and procedures in user institutions)
Species and weight g |
Minimum surface per bird cm 2 |
Minimum surface for 2 birds cm 2 |
Minimum surface for 3 or more birds 2 /Bird |
Minimum height of the cage cm |
Minimum feeder length per bird cm |
Chickens |
|||||
100-300 |
250 |
200 |
150 |
25 |
3 |
300-600 |
500 |
400 |
300 |
35 |
7 |
600-1200 |
1000 |
600 |
450 |
45 |
10 |
1200-1800 |
1200 |
700 |
550 |
45 |
12 |
1800-2400 |
1400 |
850 |
650 |
45 |
12 |
(Adult Male) |
|||||
> 2400 |
1800 |
1200 |
1000 |
60 |
15 |
Sizes 120-140 |
350 |
250 |
200 |
15 |
4 |
Note: "Surface" means the product of the length and width of the cage measured from the inside and horizontally, NOT the product of the length and width of the ground of the cage.
For the definition of "cage height", see the note in Table 6.
The openings of mesh in grilled soils should not exceed 10 x 10 mm for chicks and 25 x 25 mm for young birds and adults. The diameter of the wire should be at least 2 mm. Soil tilt should not exceed 14 % (8 °). Watering should be the same length as the feeders. When tetinal troughs or cups are used, each bird should have access to two tetinal troughs or two cups. The cages should be equipped with perches and allow birds in separate cages to see themselves.
Mouse
(storage and procedures)
Minimum Cage Surface Area
Given the weight of a mouse, the full EU-EU line gives the minimum surface the mouse should have.
Rats
(storage and procedures)
Minimum Cage Surface Area
Given the weight of a rat, the full EU-EU line gives the minimum surface the rat should have.
Hamsters of Syria
(storage and procedures)
Minimum Cage Surface Area
Given the weight of a Syrian hamster, the full EU-EU line gives the minimum surface the Syrian hamster should have.
Cobayes
(storage and procedures)
Minimum Cage Surface Area
Given the weight of a guinea pig, the full EU-EU line gives the minimum surface that the guinea pig should have.
Rabbits
(storage and procedures)
Minimum Cage Surface Area
Given the weight of a rabbit, the full EU-EU line gives the minimum surface the rabbit should have.
Rabbits
(reproduction)
Minimum ground surface of the cage for a lapine with its unweaned litter
Given the weight of a rabbit, the full line, EU-EU, gives the minimum surface that the rabbit should have.
Chats
(storage and procedures)
Minimum Cage Surface Area
Given the weight of a cat, the full EU-EU line gives the minimum area the cat should have.
Indications for the relationship between the number of mice per cage and the ground surface of the cage
(storage and procedures)
The lines represent average weights and correspond to the EU-EU line in Chart 1.
Indications for the relationship between the number of rats per cage and the ground surface of the cage
(storage and procedures)
The lines represent average weights and correspond to the EU-EU line in Chart 2.
Indications for the relationship between the number of hamsters per cage and the ground surface of the cage
(storage and procedures)
The lines represent average weights and correspond to the EU-EU line in Chart 3.
Indications for the relationship between the number of guinea pigs per cage and the ground surface of the cage
(storage and procedures)
The lines represent average weights and correspond to the EU-EU line in Chart 4.
Indications for the relationship between the number of rabbits per cage and the ground surface of the cage
(storage and procedures)
The lines represent average weights and correspond to the EU-EU line in Chart 5.
Under Art. 27 and 28 of the Convention, each Party shall compile statistical data relating to certain aspects of the procedures referred to in the Convention, and shall communicate such information to the Secretary General of the Council of Europe, who shall publish them.
It is up to each Party to choose the method used to collect the data, and there is, of course, no objection to the collection of supplementary statistical data for national needs. In order to facilitate the task of the Secretary General, however, the data provided must be comparable and correspond to the attached tables. The data are collected by calendar year.
The animals to be counted are those which are intended to be used in a manner likely to cause them lasting damage, pain, suffering or anguish (see art. 1.2.c of the Convention). Counting occurs when animals are used in a procedure. Each animal is counted only once in the same table. Animals which are not subject to procedures of the type defined in Art. 1.2.c shall not be counted for the purposes of collating statistical information under this Convention.
Because of the very nature of biological research, it is inevitable that there should be cases where it is difficult to determine in which column of a table an animal that is used in a procedure should be entered. There is no good or bad way to solve the problem; it is a matter of personal choice. Subject to the directives that the competent authorities may give, it is for the scientist to determine under what heading the animal should be included.
However, it is essential to ensure that no animals are counted twice in the same table.
Table 1
Number and kinds of animals used in procedures
In this table, the total number of animals used in procedures is mentioned, this total being broken down by type or classes of animals.
Table 2
Number of animals used in procedures for selected purposes
The purpose of this table is to show the number of animals used in the following main areas: basic research, development of new products, safety tests, disease diagnosis, education and training. In column 1, the word "medical" includes veterinary medicine.
Table 3
Number of animals used in procedures for selected purposes for the protection of humans, animals and their environment through toxicology tests or other safety tests
The purpose of this table is to provide a more detailed presentation of the procedures for the general protection of humans, animals and the environment, excluding medical purposes. Column 6 includes harmful radiation.
Table 4
Number of animals used in procedures for diseases or disorders
The purpose of this table is to indicate the number of animals used for medical purposes, including veterinary medicine, with a special reference to three areas of human disease that are of particular concern to the public.
Table 5
Number of animals used in procedures required by legislation
The column "Party concerned only" is satisfied only where the procedure is required by the law of the Party in which the procedure is carried out, including the international obligations to which that Party is subject (e.g. As a Party to the Convention on the Development of a European Pharmacopoeia 1 Or as a Member State of the European Communities).
The column "Other Parties Only" is completed if the procedure is specifically designed to meet the requirements of countries other than the Party, including trade and convention requirements, to which it is not a party.
The "Both" section is used when the procedure is intended to satisfy the requirements of both groups; in this case, no mention is made in the other two columns.
Table 1
Number and kinds of animals used in proceedings in ... (year) in ... (Part)
Mouse (Mus musculus) |
|
Rats (Rattus norvegicus) |
|
Cobayes (Cavia porcellus) |
|
Other rodents (altri Rodentia) |
|
Rabbits (Oryctolagus cuniculus) |
|
Anthropoid Singes (Hominoidea) |
|
Other simians (Cercopithecoidea e Ceboidea) |
|
Prosimians (Prosimia) |
|
Dogs (Canis Familiaris) |
|
Chats (Felis Catus) |
|
Other carnivores (altri Carnivora) |
|
Horses, donkeys and crosses (Equidae) |
|
Swine (Sus) |
|
Caprins and sheep (Capra e Ovis) |
|
Cattle (Bos) |
|
Other mammals (altri Mammalia) |
|
Birds (Aves) |
|
Reptiles (Reptilia) |
|
Amphibians (Amphibia) |
|
Fish (Pisces) |
|
Total |
|
Table 2
Number of animals used in procedures for selected purposes in ... (year) in ... (Part)
All species |
Selected species |
|||
Rodents and rabbits |
Dogs and cats |
Primates |
||
1 |
Biological (including medical) studies of a fundamental nature |
|||
2 |
Discovery, development and quality control (including safety testing) of human and veterinary medicine products or devices |
|||
3 |
Diagnosis of diseases |
|||
4 |
Protection of humans, animals and the environment through toxicology tests or other safety tests |
|||
5 |
Education and training |
|||
Table 3
Number of animals used in procedures for selected purposes for the protection of humans, animals and the environment through toxicology tests or safety tests carried out in ... (year) in ... (Part)
Detailed classification of item 4 of Table 2 |
All species |
Selected species |
||
Rodents and rabbits |
Dogs and cats |
Primates |
||
1 |
Substances used or intended for use primarily in agriculture |
|||
2 |
Substances used or intended for use primarily in industry |
|||
3 |
Substances used or intended for use primarily as cosmetics or personal hygiene products |
|||
4 |
Substances used or intended for use primarily as cosmetics or personal hygiene products |
|||
5 |
Substances used or intended for use as food additives for the use of human consumption |
|||
6 |
Actual Potential Risks of Contaminants in the General Environment |
|||
Table 4
Number of animals used in procedures for diseases or disorders in ... (year) in ... (Part)
All species |
Selected species |
|||
Rodents and rabbits |
Dogs and cats |
Primates |
||
1 |
Cancer (excluding carcinogens) |
|||
2 |
Cardiovascular Disease |
|||
3 |
Nervous and mental disorders |
|||
4 |
Other human and animal diseases |
|||
Note: When a procedure relates to cancer under all headings from 2 to 4, the cancer classification should preferably be applied.
Table 5
Number of animals used in procedures required by the legislation in ... (year) in ... (Part)
All species |
Selected species |
|||
Rodents and rabbits |
Dogs and cats |
Primates |
||
Party concerned only |
||||
Other Parties only |
||||
Both |
States Parties |
Ratification |
Entry into force |
||
Germany * |
19 April |
1991 |
1 Er November |
1991 |
Belgium |
20 December |
1991 |
1 Er July |
1992 |
Bulgaria |
July 20 |
2004 |
1 Er February |
2005 |
Cyprus |
9 December |
1993 |
1 Er July |
1994 |
Denmark * |
8 September |
2000 |
1 Er April |
2001 |
Spain |
12 September |
1989 |
1 Er January |
1991 |
Finland |
14 June |
1990 |
1 Er January |
1991 |
France * |
5 June |
2000 |
1 Er December |
2000 |
Greece |
27 May |
1992 |
1 Er December |
1992 |
Latvia * |
5 October |
2010 |
1 Er May |
2011 |
Lithuania |
14 June |
2007 |
1 Er January |
2008 |
Macedonia * |
22 January |
2004 |
1 Er August |
2004 |
Norway |
July 9 |
1986 |
1 Er January |
1991 |
Netherlands * A |
21 January |
1997 |
1 Er August |
1997 |
Czech Republic * |
20 March |
2003 |
1 Er October |
2003 |
Romania |
16 November |
2006 |
1 Er June |
2007 |
United Kingdom * |
17 December |
1999 |
1 Er July |
2000 |
Serbia |
2 December |
2010 |
1 Er July |
2011 |
Slovenia * |
15 December |
2006 |
1 Er July |
2007 |
Sweden |
September 15 |
1988 |
1 Er January |
1991 |
Switzerland |
3 November |
1993 |
1 Er June |
1994 |
|
April 30 |
1998 |
1 Er November |
1998 |
* |
Reservations and declarations. Reservations and declarations are not published in the RO. The texts in English and French can be found at the Council of Europe website: http://conventions.coe.int or obtained from the Directorate of Public International Law (DDIP), International Treaty Section, 3003 Berne. |
|||
A |
For the Kingdom in Europe. |
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1 See also art. 30 to 38 modified by art. 1-3 prot. Of am. On 22 June 1998, in force for Switzerland since 2 December 1998. 2005 (RS 0.457.1 ).
2 Art. 1 al. 1 let. B of the AF of 17 June 1993 (RO 1994 918).
3 RO 1994 981, 2004 5001, 2010 3255, 2013 1241. A version of the updated scope of application is published on the DFAE website (www.dfae.admin.ch/traites).