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Article 12 of the Organic Law of 21 November, on the protection of health and the fight against doping in sport, establishes the obligation of the Superior Council of Sports to publish in the "Official Gazette of the State", by means of a resolution of its Presidency, the list of substances and methods prohibited in sport when changes are made to it. The article also provides that such publication shall be carried out within the framework of the international commitments and obligations assumed by Spain, and in particular within the framework of the UNESCO Anti-Doping Convention.

In accordance with the specific procedure of Article 34 of the International Convention against Doping in Sport, made in Paris on 18 November 2005 (published in the Official Gazette of 16 February 2005). 2007), the conference of the parties to the convention has approved the amendment to Annex I, the list of substances and methods prohibited in sport.

Accordingly, and in order to adapt the previous list of prohibited substances and methods in sport, approved by Resolution of 23 December 2010 from the Presidency of the High Council of Sport, to the list adopted in The International Convention against Doping in Sport of UNESCO, this Higher Council of Sports resolves to approve the list of substances and methods prohibited in sport, contained in the Annexes to this Resolution.

This Resolution will apply to doping control procedures in sport that are performed in official state-wide competitions or, outside of them, to athletes with a license to participate in such competitions. competitions.

The previous list approved by Resolution of 23 December 2010 of the Presidency of the Higher Council of Sports is hereby repealed.

Annexes IV and V to the Resolution of 21 December 2006 of the Presidency of the High Council for Sport, approving the list of substances and methods prohibited in sport, relating to the list of substances and Methods prohibited in animals, greyhounds and equestrian competitions, respectively, remain in force, in accordance with the provisions of the first provision of the Organic Law of 21 November of 21 November, of protection of health and the fight against doping in sport.

Madrid, 30 November 2011.-The President of the Superior Council of Sports, P. D. (Royal Decree 2195/2004, of 25 November), the Director General of Sports, Matilde García Duarte.

ANNEX I

List of prohibited substances and methods-International standards

The 2012 list of bans on world anti-doping code (this list will enter into force on January 1, 2012).

Under the provisions of Article 4.2.2 of the World Anti-Doping Code, all prohibited substances must be considered as 'specific substances', with the exception of substances belonging to categories S1, S2, S4.4, S4.5 and S6 (a) and the prohibited methods M1, M2 and M3.

Prohibited substances and methods at all times (in and out of competition)

Prohibited substances

S0. Substances without approval.

Any pharmacological substance that is not included in any of the following sections of the list is prohibited at all times and is not currently approved by any government health regulatory authority for use. human therapeutic (e.g., pre-clinical or clinical or suspended medicinal products, synthetic drugs, veterinary medicinal products).

S1. Anabolic agents.

Anabolic agents are prohibited.

S1.1 Androgenic Anabolic Steroids (EAA)

a) Exogenous EAA *, including:

1-androstenediol (5α-androst-1-en-3β, 17β-diol); 1-androstendione (5α-androst-1-en-3,17-dione); bolandiol (estr-4-ene-3β, 17β-diol); bolasterone; boldenone; boldione (androsta-1,4-dien-3,17-dione); calusterone; clostebol; danazol (17α-ethinyl-17β-hydroxyandrost-4-en [2,3-d] isoxazole); dehydrochlormethyltestosterone (4-chloro-17β-hydroxy-17α-methylandrosta-1,4-dien-3-one); desoxymethyltestosterone (17α-methyl-5α-androst-2-en-17β-ol); drostanolone; estanozolol; stembolone; ethylenediol (19-nor-17α-pregn-4-en-17-ol); fluoxysterone; formebolone; furazabol (17β-hydroxy-17α-methyl-5α-androstan [2,3-c]-furazan); gestrinone; 4-hydroxytestosterone (4,17β-dihydroxyandrost-4-en-3-one); mstanolone; mesterolone; methandienone (17β-hydroxy-17α-methylandrosta-1,4-dien-3-one); methandriol; metasterone (2α, 17α-dimethyl-5α-androstan-3-ona-17β-ol); methenolone; methyldienolone (17β-hydroxy-17α-methylestra-4,9-dien-3-one); methyl-1-testosterone (17β-hydroxy-17α-methyl-5α-androst-1-en-3-one); methylnortestosterone (17β-hydroxy-17α-methylestr-4-en-3-one) methyltestosterone, metribolone (methyltrienolona, 17β-hydroxy-17α-methylestra-4,9,11-trien-3-one); mibolerone; nandrolone; 19-norandrostendione (ester-4-en-3,17-dione); norboletone; norclostebol; norethandrolone; oxabolone; oxandrolone; oxymorsterone; oxymetholone; prostanozol (17β-hydroxy-5α-androstan [3,2-c] pyrazole); quinbolone; 1-testosterone (17β-hydroxy-5α-androst-1-en-3-one); tetrahydrogestrinone (18-homo-pregna-4,9,11-trien-17β-ol-3-one); braid, and other chemicals or similar biological effects.

b) endogenous EAA * * when administered externally:

Androstendiol (androst-5-en-3β, 17β-diol); androstendione (androst-4-en-3,17-dione); dihydrotestosterone (17β-hydroxy-5α-androstan-3-one); prasterone (dehydroepiandrosterone, DHEA); testosterone and its metabolites and isomers, they, but not exclusively:

5α-androstan-3α, 17α-diol; 5α-androstan-3α, 17β-diol; 5α-androstan-3β, 17α-diol; 5α-androstan-3β, 17β-diol; androst-4-en-3α, 17α-diol; androst-4-en-3α, 17β-diol; androst-4-en-3β, 17α-diol; androst-5-en-3α, 17α-diol; androst-5-en-3α, 17β-diol; androst-5-en-3β, 17α-diol; 4-androstendiol (androst-4-en-3β, 17β-diol); 5-androstendione (androst-5-en-3,17-dione); epi-dihydrotestosterone sterone; epittestosterone; 3α-hydroxy-5α-androstan-17-one; 3β-hydroxy-5α-androstan-17-one; 7α-hydroxy-DHE; 7β-hydroxy-DHEA; 7-keto-DHEA, 19-norandrosterone; 19-norethocolanolone.

For purposes of this section:

* "exogenous" refers to a substance that, by common, the body cannot produce naturally.

** "endogenous" refers to a substance that the body can produce naturally.

S1.2 Other anabolic agents, including but not limited to:

Clenbuterol, selective androgen receptor modulators (MRSA), tibolone, zeranol, zilpaterol.

S2. Peptide hormones, growth factors and related substances.

The following substances and their release factors are prohibited:

1. Erythropoiesis stimulating agents [p. e.g., erythropoietin (EPO), darbepoetin (dEPO), hypoxia inducible factor stabilizers (HIF), methoxy polyethylene glycol-epoetin beta (CERA), peginesatide (Hematide)];

2. Chorionic gonadotrophin (CG) and luteinizing hormone banned only in men;

3. Insulins;

4. Corticotrophins;

5. Growth hormone (GH), growth factor analogue to insulin-1 (IGF-1), fibroblastic growth factors (FGF), hepatocyte growth factor (HGF), mechanical growth factors (FGM), growth factor derived from the platelets (PDGF) and vascular endothelial growth factor (VEGF), as well as any other growth factor affecting the muscles, tendons or ligaments, to the synthesis or degradation of the proteins, to vascularization, to the use of the energy, the capacity for regeneration or the modification of the type of fibre; and other substances with a similar chemical structure or biological effect (s).

S3. Beta-2 agonists.

All beta-2 agonists (including their two optical isomers where appropriate) are prohibited except salbutamol (maximum amount of 1,600 micrograms in 24 hours), formoterol (maximum amount of 36 micrograms in 24 hours). hours) and salmeterol, if administered by inhalation, for therapeutic use, in accordance with the manufacturer's recommendations.

It is presumed that the presence in the urine of a concentration of salbutamol greater than 1,000 nanograms per milliliter or of formoterol greater than 30 nanograms per milliliter does not correspond to a therapeutic use of the substance and consider the analytical result as adverse unless the athlete demonstrates, by a controlled pharmacokinetic study, that this adverse outcome was a consequence of the use of the inhaled therapeutic dose reaching the maximum amount indicated above.

S4. Hormone modulators and metabolism.

The following are prohibited:

1. Aromatase inhibitors, including but not limited to: aminogluteshy, anastrozole, androsta-1,4,6-trien-3,17-dione (androstatrienedione), 4-androsten-3,6,17 trione (6-oxo), exemestane, formtin, letrozole, testolactone;

2. Selective estrogen receptor modulators (SERM), which include but are not limited to: raloxifene, tamoxifen, toremifene;

3. Other antiestrogenic substances, including but not limited to: clomifene, cyclofenil, fulvestrant;

4. Agents that modify the function (s) of myostatin, which include but are not limited to: myostatin inhibitors;

5. Metabolism modulators: receptors activated by the peroxisomes δ (PPARδ) proliferators (e.g., GW 1516), PPARδ-protein kinase-activated protein kinase (AMPK) agonists (e.g., AICAR).

S5. Diuretics and other masking agents.

The masking agents are prohibited. They comprise:

Diuretics, desmopressin, plasma expanders (p. (e. g., glycerol, intravenous administration of albumin, dextran, hydroxyethylstarch and mannitol), probenedate, and other substances with similar biological effect (s). Local application of felipresin in dental anesthesia is not prohibited.

Diuretics comprise: acetazolamide, etacrinic acid, amiloride, bumetanide, canrenone, chlorthalidone, spironolactone, furosemide, indapamide, metolazone, thiazides (p. e.g. bendroflumetiazide, chlordimethide, hydrochlorothiazide), triamterene, and other substances with a similar chemical structure or biological effect (s) (with the exception of barking, pamabrim, topical dorzolamide and brinzolamide, which are not prohibited).

The use, in competition or out of competition, as appropriate, of any amount of a substance subject to threshold levels (formoterol, salbutamol, morphine, catina, ephedrine, methylefedrine and pseudoephedrine) in combination with a diuretic or other masking agent requires the obtaining of a therapeutic authorisation for that substance, in addition to that granted for the diuretic or the other masking agent.

Prohibited Methods

M1. Increased oxygen transfer.

The following is prohibited:

1. Blood doping, including the use of autologous, homologous or heterologous blood or red blood products of any origin;

2. The artificial improvement of the uptake, transport or transfer of oxygen, which includes but is not limited to: perfluorinated chemicals, efaproxiral (RSR13) and modified hemoglobin products (p. E. g. blood substituents consisting of hemoglobin, products based on microencapsulated hemoglobins), excluding supplemental oxygen.

M2. Chemical and physical handling.

The following is prohibited:

1. The falsification, or the attempt to falsify the samples taken during the doping controls, in order to alter their integrity and validity. This includes, but is not limited to the substitution and/or adulteration of urine (p. e.g. proteases);

2. Intravenous infusions and/or injections of more than 50 millilitres per 6-hour interval, except those received legitimately in the course of hospital admissions or clinical reviews;

3. The successive extraction, manipulation and reintroduction of any amount of blood in the circulatory system.

M3. Genetic doping.

The following activities that can improve sports performance are prohibited:

1. The transfer of nucleic acids or nucleic acid sequences;

2. The use of normal or genetically modified cells.

Prohibited substances and methods in competition

In addition to the S0 to S5 and M1 categories to M3 that have been previously defined, the following categories are prohibited in competition:

Prohibited substances.

S6. Stimulants.

All stimulants (including their two optical isomers where appropriate) are prohibited, except for topical imidazole derivatives and stimulants included in the 2012 Tracking Program *.

Stimulants comprise:

a) Non-specific stimulants:

Adrafinil, amifenazole, anfepramone, amphetamine, amphetamine, benfluorex, benzfetamine, benzylpiperazine, bromantan, clobenzorex, cocaine, cropropamide, crotetamide, dimethylamphetamine, ethylamphetamine, famprofazone, phenamine, fendimethazine, phenetylin, 4-phenylpyracetam (carfedon), fenfluramine, phenmethazine, fenotrix, phentermine, furfenenex, mefenedix, mephentermine, mesocarb, methamphetamine (d-), p-methylamphetamine, methylenedioxyamphetamine, methylenedioxymethetamine,), modafinil, norfenfluramine, prenylamine and prolinane.

A stimulant that is not expressly mentioned in this section is a Specific Substance.

b) Specific stimulants (examples):

Adrenaline * *, catina * **, ephedrine * ***, stricngirl, etamivan, etilephrine, fenbutrazate, fencamfamin, fenpromethamine, heptaminol, isometepteno, levmethamphetamine, meclofenoxate, methylfedrine * ***, methylhexanamine (dimethylpentylamine), methylphenidate, niquetamide, norfenefrine, octopamine, oxilofrine, parahydroxyamphetamine, pemoline, pentetrazole, propylhexedrine, pseudoephedrine * ****, selegiline, sibutramine, tuaminoheptane, and other chemicals or effect (s) Similar biological (s).

* The following substances included in the monitoring programme 2012 (bupropion, caffeine, phenylephrine, phenylpropanolamine, nicotine, pipradol, sinephrine) are not considered to be prohibited substances.

** Local administration is not prohibited (p. (e. g. nasal, ophthalmologic) of adrenaline and its administration associated with local anesthetic agents.

*** Catina is prohibited when its concentration in urine exceeds 5 micrograms per millilitre.

**** Both ephedrine and methylefedrine are prohibited when their urine concentration exceeds 10 micrograms per millilitre.

***** Pseudoephedrine is prohibited when your urine concentration exceeds 150 micrograms per millilitre.

S7. Narcotics.

The following are prohibited:

Buprenorphine, dextromoramide, diamorphine (heroin), fentanyl and its derivatives, hydromorphone, methadone, morphine, oxycodone, oxymorphone, pentazocine, pethidine.

S8. Cannabinoids.

Natural delta9-tetrahydrocannabinol (THC) (e.g., cannabis, hashish, marijuana) or synthetic and cannabimimics [e.g. "Spice " (containing JWH018, JWH073), HU-210] are prohibited.

S9. Glucocorticosteroids.

All glucocorticosteroids are prohibited when administered orally, intravenously, intramuscularly or rectal.

Banned substances in certain sports

P1. Alcohol.

Alcohol (ethanol) is only banned in competition in the sports mentioned below. Detection will be done by breath and/or blood tests. The violation threshold (hematological values) is 0.10 grams per liter.

Aeronautics (FAI).

Motoring (FIA).

Karate (WKF).

Motorcycling (FIM).

Motontics (UIM).

Archery (FITA, CPI).

P2. Beta-blockers.

Unless otherwise specified, beta-blockers are only prohibited in competition in the following sports.

Aeronautics (FAI).

Motoring (FIA).

Billiards (all disciplines) (WCBS).

Bowling (CMSB).

Bridge (FMB).

Darts (WDF).

Skiing/Snowboarding (FIS) in jumps, acrobatics and ski-freestyle halfpipe, and halfpipe and snowboard Big Air.

Golf (IGF).

Motontics (UIM).

Nine bowling and ten bowling (FIQ).

Shooting (ISSF, CPI) (also prohibited outside the competition).

Archery (FITA) (also prohibited outside the competition).

Beta-blockers include, but not exclusively, the following substances:

Acebutolol, alprenolol, atenolol, betaxolol, bisoprolol, bunolol, carteolol, carvedilol, coeliprolol, esmolol, labetalol, levobunolol, metipranolol, metoprolol, nadolol, oxprenolol, pindolol, propranolol, sotalol, timolol.