For the purposes of this Agreement, the term "tissue group determination reagents" means all reagents for the determination of tissue groups of human, animal, plant or other origin.

2. The provisions of s. 2 to 6 of this Agreement also apply to known antigenic composition cells used for the study of the reagents in question.

The Contracting Parties undertake, provided that they have sufficient reserves for their own needs, to make the reagents for the determination of the tissue groups available to other Parties who need them, without any further Compensation that is necessary for the reimbursement of the costs of collection, preparation and transport of such substances and, where applicable, the costs of the purchase thereof.

The reagents for the determination of tissue groups shall be made available to the other Contracting Parties under the conditions that they will not give rise to any benefit and shall be used solely for medical and scientific purposes, Non-commercial, and may only be delivered to the laboratories designated by the governments concerned in accordance with Art. 6 of this Agreement.

The Contracting Parties shall ensure compliance with the provisions as defined in the Protocol ¹ To this Agreement.

2. They shall also comply with the rules to which they have acceded in the field of international standardisation in this field.

3. Any shipment of reagents for the determination of tissue groups shall be accompanied by a certificate attesting that it has been prepared in accordance with the specifications of the Protocol. The certificate will be prepared in accordance with the model set out in the Annex to the Protocol.

The Protocol and its Annex shall have the character of an administrative arrangement and may be amended or supplemented by the Governments of the Parties to this Agreement.

1. The Contracting Parties shall take all necessary measures to exempt from all import rights the reagents for the determination of tissue groups made available to them by the other Parties.

2. They shall also take all necessary measures to ensure, through the most direct route, the rapid delivery of these substances to the recipients referred to in Art. 3 of this Agreement.

The Contracting Parties shall, through the Secretary General of the Council of Europe, communicate the list of national and/or regional reference laboratories entitled to establish the certificate provided for in Art. 4 of this Agreement and to distribute the imported tissue grouping reagents.

1. This Agreement shall be open for signature by the member States of the Council of Europe which may become Parties to this Agreement by:

A.

Signature without reservation of ratification or acceptance, or

B.

Signature subject to ratification or acceptance followed by ratification or acceptance.

2. Instruments of ratification or acceptance shall be deposited with the Secretary General of the Council of Europe.

1. This Agreement shall enter into force one month after the date on which three member States of the Council have become Parties to the Agreement, in accordance with the provisions of Art. 7.

2. For any Member State which subsequently signs it without reservation as to ratification or acceptance or ratifies or accepts it, the Agreement shall enter into force one month after the date of signature or deposit of the instrument of ratification or Of acceptance.

After the entry into force of this Agreement, the Committee of Ministers of the Council of Europe may invite any non-member State of the Council to accede to it.

2. Accession shall be effected by the deposit, by the Secretary General of the Council of Europe, of an instrument of accession which shall take effect one month after the date of its deposit.

(1) Any Contracting Party may, at the time of signature or at the time of deposit of its instrument of ratification, acceptance or accession, designate the territory or territories to which this Agreement shall apply.

2. Any Contracting Party may, at the time of the deposit of its instrument of ratification, acceptance or accession or at any other time thereafter, extend the application of this Agreement by declaration addressed to the Secretary General of the Council of Europe, in any other territory designated in the declaration for which it is responsible for international relations or for which it is entitled to stipulate.

(3) Any declaration made under the preceding paragraph may be withdrawn, in respect of any territory designated in that declaration, under the conditions laid down in Art. 11 of this Agreement.

1. Any Contracting Party may, as far as it is concerned, denounce this Agreement by sending a notification to the Secretary General of the Council of Europe.

The denunciation shall take effect six months after the date of receipt of the notification by the Secretary General.

The Secretary General of the Council of Europe shall notify the member States of the Council and any State which has acceded to this Agreement:

A.

Any signature without reservation of ratification or acceptance;

B.

Any signature with reservation of ratification or acceptance;

C.

The deposit of any instrument of ratification, acceptance or accession;

D.

Any date of entry into force of this Agreement pursuant to the provisions of Art. 8;

E.

Any statement received pursuant to the provisions of s. 2 and 3 of Art. 10;

F.

Any notification received pursuant to the provisions of Art. 11, and the date on which the denunciation takes effect;

G.

Any amendment or supplement to the Protocol and its Annex under s. 4 of Art. 4 of this Agreement.

In witness whereof, The undersigned, duly authorized to that effect, have signed this Agreement.

Done at Strasbourg, on 17 September 1974, in English and in French, both texts being equally authentic, in a single copy which shall be deposited in the archives of the Council of Europe. The Secretary General of the Council of Europe shall transmit certified copies to each of the signatory and acceding States.

(Suivent signatures)