(art. 5 of the Convention)

1. The member states of the Council of Europe have decided that they propose to protect live animals used for experimental and other scientific purposes, to ensure that lasting damage, pain, suffering or The anguish they suffer as consequences of procedures on them are limited to the bare minimum.

2. It is true that certain procedures are carried out on the ground with wild animals living in freedom and providing for their own subsistence, but they are, however, very limited. The vast majority of animals used in the proceedings must, for practical reasons, be maintained under any physical control in facilities ranging from outside the park to small animal cages in a pet shop. Laboratory. In this situation, many interests are in conflict. On the one hand there is the animal, whose needs for movement, social relations and other manifestations of life must be restricted, on the other hand, the experimenter and its assistants, which require full control of the animal and its environment. In this conflict of interest, it can sometimes only be of secondary interest to the animal.

3. Therefore, the European Convention on the Protection of Vertebrate Animals used for experimental or other scientific purposes provides in its art. " Any animal used or intended for use in a proceeding shall benefit from housing, an environment, at least a certain freedom of movement, food, water and care appropriate to its health and well-being. Any restriction on its ability to meet its physiological and ethological needs is limited as much as possible."

4. This appendix contains a number of guidelines based on current knowledge and practice related to accommodation and animal care. It explains and supplements the basic principles adopted in art. 5. The aim is to help the authorities, institutions and individuals in their pursuit of the objectives of the Council of Europe.

5. The word "care", used in relation to animals used or intended for use in procedures, covers all aspects of the relationship between the animal and man. It covers all material and other resources mobilized by man to obtain and maintain an animal in a physical and mental state where it suffers as little as possible and bears the best support for procedures. Care must be taken from the time the animal is chosen for use in proceedings until the animal is sacrificed by a humanitarian method or otherwise by the establishment at the end of the procedure, in accordance with the Provisions of s. 11 of the Convention.

6. The purpose of the Annex is to provide advice on the structure of premises for animals. However, there are several methods of rearing and maintaining laboratory animals that differ primarily in the degree of control of the microbiological environment. It must be kept in mind that the staff concerned will sometimes have to be able to judge the character and conditions of the animals when the recommended standards of space may be insufficient, for example with animals Particularly aggressive. The application of the guidelines in this Annex should take into account the requirements of these different situations. In addition, the status of these guidelines should be clarified. Unlike the provisions of the Convention, they are not binding: they are discretionary recommendations intended to serve as a guide to practices and standards to which all concerned Should make a conscious effort to achieve this. It is for this reason that the word "devrai (en) t" had to be used throughout the text, even when the word "must (must)" seemed more appropriate. It is obvious, for example, that food and water Must Be provided (see 3.7.2 and 3.8).

Finally, for practical and financial reasons, existing animal facilities should not be replaced as long as they are in good condition or have not become unnecessary in any other way. Pending replacement by installations that comply with the suggested guidelines, they should be observed as far as possible by adapting the number and size of the animals to the existing cages and enclosures.

For the purposes of Schedule A, in addition to the definitions contained in s. 1.2 of the Convention:

A.

Accommodation: Rooms where the animals are normally lodged, either for breeding and rearing, or during the course of a procedure;

B.

Cage: Fixed or movable space enclosed by solid walls, of which at least one wall consists of bars or wire mesh or, if necessary, nets and in which one or more animals are kept or transported; according to the rate of Stand and dimensions of the cage, the freedom of movement of animals is more or less restricted;

C.

Enclosure (box): Surface surrounded by, for example, walls, bars or wire mesh in which one or more animals are kept; although function of the dimensions of the enclosure and the rate of stand, the freedom of movement of animals is usually Less restricted than in a cage;

D.

Outdoor enclosure: Surface surrounded by, for example, a fence, walls, bars or wire mesh and frequently located outside a fixed construction, in which animals kept in cages or enclosures can move freely during some Periods of time in accordance with their ethological and physiological needs, such as taking exercise;

E.

Stall: A small compartment on three sides, normally equipped with a feeder and side separations and where one or two animals may be attached.

1.1. Functions and General Design

1.1.1. Every facility should be designed to provide an appropriate environment for the species in the facility. It should also be designed to prevent unauthorized access.

Facilities that are integrated into a larger building should also be protected by adequate construction standards and provisions limiting the number of entrances and preventing the movement of unauthorized persons.

1.1.2. It is recommended that a facility maintenance program be used to prevent equipment failure.

1.2. Accommodation Premises

1.2.1. All necessary measures should be taken to ensure the prompt and effective cleaning of premises and the maintenance of adequate hygiene standards. The ceilings and walls should be resistant and provide a smooth, waterproof and easily washable surface. Particular attention should be paid to the joints of doors, pipes, pipes and cables. The doors and, where appropriate, windows should also be constructed or protected in such a way as to prevent access to undesirable animals. If necessary, an oculus can be arranged in the door. The floor should be smooth, impermeable, with a non-slippery surface and easy to wash, capable of withstanding the weight of lockers and other heavy installations without damage. Where escape vents exist, they should be properly covered and equipped with a grid to prevent the penetration of animals.

1.2.2. Premises where animals can move freely should have walls and floors covered with a coating that is particularly resistant to bear the significant wear and tear caused by the animals and the cleaning. This coating should not be harmful to the health of animals and designed to prevent injury. Evacuation balls are desirable on such premises. Additional protection should be provided for equipment or facilities so that they cannot be damaged by animals or harm the animals themselves. If there are external enclosures, the necessary measures should be taken, if necessary, to prevent public and animal access.

1.2.3. Premises for farm animals (cattle, sheep, goats, pigs, horses, poultry, etc.) should at least comply with the standards set out in the European Convention on the Protection of Animals in Farming ¹ And by the national veterinary and other authorities.

1.2.4. The majority of animal facilities are usually designed to house rodents. Very often these premises can also be used to house larger species. Care should be taken not to cohabit incompatible species.

1.2.5. Premises where animals are housed should be equipped with facilities, where appropriate, for the implementation of minor procedures and handling.

1.3. Laboratories and general and special procedure rooms

1.3.1. In livestock establishments or suppliers, appropriate facilities for the preparation of shipments of animals ready for shipment should be available.

1.3.2. All establishments should also have at least laboratory facilities to establish simple diagnoses, conduct examinations Post-mortem, And/or collect samples for further laboratory tests that will be carried out elsewhere.

1.3.3. Provisions should be made for the reception of animals in such a way that they, upon their arrival, do not endanger the animals already present in the facility, for example by quarantine. General and special procedural rooms should be available for cases where procedures or observations are not desirable in the room where the animals are housed.

1.3.4. Appropriate facilities should be available to allow sick or injured animals to be housed separately.

1.3.5. Where appropriate, it would also be appropriate to have one or more separate operating rooms, equipped in such a way as to permit surgical procedures under aseptic conditions. Premises should be available to allow the animals to recover after an operation when necessary.

1.4. Service Premises

1.4.1. The premises used to store food should be fresh, dry, protected from vermin and insects, and those used for bedding should be dry and protected from vermin and insects. Other materials that could be contaminated or could present a risk should be kept separate.

1.4.2. Premises should be available for storage of clean cages, instruments and other equipment.

1.4.3. The cleaning and washing facilities should be spacious enough to contain the equipment necessary for decontamination and cleaning of the equipment used. The cleaning circuit should be arranged in such a way as to separate the passage from clean and dirty equipment in order to avoid contamination of the equipment that has just been cleaned. The walls and floor should be covered with an appropriate resistance and the ventilation system powerful enough to remove excessive heat and humidity.

1.4.4. Provision should be made for storage in satisfactory hygiene conditions and for the disposal of carcasses and animal waste. If on-site incineration is not possible or desirable, appropriate arrangements should be made for the disposal of these substances in accordance with local regulations and orders. Special precautions should be taken with highly toxic or radioactive waste.

1.4.5. The design and construction of traffic areas should be consistent with animal housing standards. Corridors should be wide enough to allow easy movement of rolling stock.

2.1. Breakdown

2.1.1. The accommodation facilities of the animals should have a ventilation system appropriate to the requirements of the hosted species. The purpose of the ventilation system is to provide clean air and reduce odours, toxic gases, dust and infection agents of any kind. Another objective is to contribute to the elimination of excessive heat and humidity.

2.1.2. Air on the premises should be renewed frequently. A ventilation rate of 15 to 20 air renewals per hour is generally sufficient. However, in some circumstances, when stand density is low, a ventilation rate of 8 to 10 air renewals per hour may be sufficient and mechanical ventilation may even be unnecessary. In other cases, it may be necessary to have more frequent renewal. Untreated air recirculation should in any case be avoided. It should be noted, however, that even the most effective system cannot compensate for poor cleaning habits or neglect.

2.1.3. Ventilation systems should be designed to avoid harmful air currents.

2.1.4. Smoking should be prohibited in the premises in which animals are found.

2.2. Temperature

2.2.1. Table 1 shows the range in which it is recommended to maintain temperature. It should also be noted that the figures apply only to adult and normal animals. Newborns and young people often need a much higher temperature. The temperature setting of the premises should take into account any changes in the thermoregulation of the animals due to particular physiological conditions or the effects of the procedures.

2.2.2. In the climatic conditions prevailing in Europe, it may be necessary to provide for a ventilation system with devices for both heating and cooling air.

2.2.3. In user establishments, the temperature of the accommodation spaces of the animals should be strictly controlled. Indeed, ambient temperature is a physical factor that has a significant effect on the metabolism of all animals.

2.3. Humidity

Extreme variations in relative humidity (RH) have an adverse effect on the health and welfare of animals. It is therefore recommended that the level of HR at the premises be appropriate for the hosted species and would normally be maintained at 55 % +/ - 10 %. Values below 40 % or above 70 % should be avoided for an extended period of time.

2.4. Lighting

In rooms without windows, it is necessary to provide controlled artificial lighting for, at the same time, to satisfy the biological requirements of animals and to provide a satisfactory working environment. It is also necessary to exercise control of the light intensity and the light-dark cycle. When albino animals are raised, their sensitivity to light should be taken into account (see also 2.6).

2.5. Noise

Noise can be an important factor in the disturbance of animal facilities. Accommodation and procedural rooms should be isolated from sources of high noise in the range of audible sounds and high frequency sounds, in order to avoid disturbance of animal behaviour and physiology. Sudden noise may result in considerable changes in organic functions but, since some noises are often unavoidable, it may be appropriate in certain circumstances to provide accommodation and Experimental rooms with a continuous sound background, of moderate intensity, such as soft music.

2.6. Alarm System

An installation housing a large number of animals is vulnerable. It is therefore recommended that facilities be properly protected by providing systems to detect fires and the entry of unauthorized persons. Technical defects or breakdowns of the ventilation system constitute another hazard which may lead to disturbance and even death of animals by suffocation or excess heat or, in the least serious cases, which may have on a procedure Negative effects to the point of making it fail and to force it to be redone. Appropriate monitoring devices should therefore be installed in connection with the heating and ventilation system to allow staff to monitor their operation in general. Where appropriate, it would be desirable to install an emergency generator to ensure the operation of animal survival and lighting equipment in the event of a failure or interruption in the supply of electricity. Clear instructions for emergency arrangements should be prominently displayed. It is recommended that an alarm system be provided in fish pens in the event of a failure of the water supply. It should be ensured that the functioning of the alarm system disrupts animals as little as possible.

3.1. Health

3.1.1. The person in charge of the establishment should ensure that a regular inspection of the animals and a control of the conditions in which they are housed and treated are carried out by a veterinarian or other competent person.

3.1.2. Due to the potential risk to animals, the health and hygiene of personnel should be given special attention.

3.2. Capturing

Wild animals and animals from stray animals should be captured only by humanitarian methods and by experienced people who have a thorough knowledge of the habits and habitats of the animals to be captured. If an anesthetic or any medication is to be used in the capture operation, it should be administered by a veterinarian or other competent person. Any severely injured animal should be presented as soon as possible to a veterinarian for treatment. If, in the opinion of the veterinarian, the animal can only survive with suffering and pain, it should be immediately sacrificed by a humanitarian method. In the absence of a veterinarian, any seriously injured animal should be immediately sacrificed by a humanitarian method.

3.3. Packaging and transport conditions

There is no doubt that transportation is a difficult test for animals that should be mitigated to the extent possible. Animals should be in good health to be transported and the consignor has a duty to control that they are transported. Animals ill or in poor condition should never be transported, except for therapeutic or diagnostic purposes. Special care should be given to pregnant females in the advanced gestational condition. Females at risk of calving off the road, or those that have calving during the previous forty-eight hours, and their offspring, should not be transported. Shipper and carrier should take all necessary precautions during packaging, loading and transit, in order to avoid unnecessary suffering caused by inadequate ventilation, exposure to temperatures Extreme, lack of food and water, long delays, etc. The consignee should be properly informed of the details of transport and the characteristics of the transport documents in order to ensure prompt handling and delivery to the place of destination. Even in the case of States not party to the European Convention on the Protection of Animals in International Transport ² , it is recommended that the provisions of the Act be strictly adhered to. It is also recommended that strict compliance with national laws and regulations, as well as live animal regulations of the International Air Transport Association and the Air Transport Association of Animals (Animal Air Transport Associ A (a) .

3.4 . Receipt and Unpacking

Packages containing animals should be recovered and unpacked without undue delay. After inspection, animals should be transferred to clean cages or pens where they will be given food and water in an appropriate manner. Animals ill or in poor physical condition should be observed and kept away from other animals. They should be reviewed as soon as possible by a veterinarian or other competent person and treated as appropriate. Animals with no chance of recovery should be immediately sacrificed by a humanitarian method. Finally, all animals received must be registered and marked in accordance with the provisions of Art. 16, 17 and 24 of the Convention. Boxes used for transportation should be destroyed immediately if decontamination facilities are not available.

3.5 Quarantine, isolation and acclimatization

3.5.1. The goals of the quarantine are:

A.

Protect other animals of the facility;

B.

Protect humans from zoonotic infections; and

C.

To develop good scientific practice.

Unless the health status of the animals entering an establishment is satisfactory, it is recommended that they be quarantined. In certain cases, such as rabies, the duration may be fixed by the national law of the Party. In other cases, it will be variable and should be determined according to the circumstances by a competent person, normally the veterinarian hired by the institution (see also Table 2).

Animals may be used for procedures during the quarantine period as long as they have acclimatized to their new environment and do not pose any significant risk to other animals or to humans.

3.5.2. It is recommended that premises be provided to isolate animals that show signs of ill health or that are suspected of being in poor health and that could pose risks to humans or other animals.

3.5.3. Even if the animals are found to be in good health, it is good zootechnical practice to have them undergo a period of acclimation before using them in a procedure. The time required depends on several factors, such as the stress experienced by the animal, which is itself a function of several factors, such as the duration of transport and the age of the animal. The duration of this period shall be decided by the competent person.

3.6 . Cage

3.6.1. Two large systems can be distinguished for the accommodation of animals. The first is the existing system in livestock establishments, suppliers and users of the bio-medical sector and intended for the accommodation of animals, such as rodents, rabbits, carnivores, birds and primates, not Humans, sometimes also ruminants, pigs and horses. Suggested guidelines for cages, paddocks (boxes), outdoor enclosures, and stalls suitable for these facilities are shown in Tables 3 to 13. Additional information on the minimum floor space of the cages can be found in diagrams 1 through 7. In addition, corresponding indications for the evaluation of the stocking density in cages are shown in diagrams 8 to 12.

Second, it is the system that often exists in establishments engaged in procedures only with farm animals or similar sized animals. The means available in such establishments should not be lower than those advocated by common veterinary standards.

3.6.2. Cages and enclosures should not be made in material that is harmful to the health of animals; they should be designed to prevent injury to animals and, unless disposable, to be constructed in a material Resistant to cleaning and decontamination techniques. Special attention should be given to the design of cage and enclosure floors, which should vary according to the species and age of the animal and be designed to facilitate the disposal of the droppings.

3.6.3. Outer enclosures should be designed for species well-being. They should allow for the satisfaction of certain ethological needs (for example, the possibility of climbing, isolating or temporarily sheltering). They should also allow for effective cleaning and avoid contact with other animals.

3.7. Feeding

3.7.1. In the choice, production and preparation of food, precautions should be taken to avoid chemical, physical and microbiological contamination. They should be packed, where appropriate, in sealed sealed bags bearing the date of manufacture. Packaging, transport and storage should be designed to avoid contamination, deterioration or destruction. Storage facilities should be cool, dark, dry, protected from vermin and insects. Perishable foods such as green fodder, vegetables, fruits, meat, fish, etc., should be stored in cold rooms, refrigerators or freezers.

All hoppers, troughs or other utensils used to feed the animals should be cleaned and, if necessary, sterilized regularly. If wet foods are used or foods are easily contaminated with water, urine, etc., daily cleaning is required.

3.7.2. The presentation of food varies depending on the species, but it should be such that it meets the physiological needs of the animal. In addition, the necessary arrangements should be made for each animal to have access to food.

3.8. Water

3.8.1. All animals must have permanently uncontaminated drinking water. During transport, it is recognized that water is supplied as part of a wet diet. However, water is a vehicle of micro-organisms, and that is why it should be provided in such a way that the risks are minimized. Two methods are commonly used, baby bottles and automatic watering systems.

3.8.2. For small animals such as rodents and rabbits, bottles are often used. When such containers are used, they should be made of a translucent material in order to control the contents. The neck should be large enough to allow for easy and effective cleaning, and if the bottle is made of plastic, it should be non-leachable. Capsules, caps and hoses should also be able to be sterilized and easy to clean. All bottles and accessories should be dismantled, cleaned and sterilized at appropriate and regular intervals. It would be preferable to replace the baby bottles with clean and sterilized bottles each time, rather than refilling them in the animal accommodation facility.

3.8.3. Automatic troughs should be regularly checked and maintained, and operation should be regularly monitored to prevent accidents and the development of infections. If compact floor cages are used, care should be taken to minimize the risk of flooding. It is also recommended that a bacteriological examination of the system be carried out regularly to control water quality.

3.8.4. Water from the public network contains a few micro-organisms that are generally considered safe, unless we work with microbiologically defined animals. In such cases, water should be treated. The water in the public supply system is generally chlorinated to limit the development of micro-organisms. This chlorination is not always sufficient to limit the growth of some potential pathogens, such as pseudomonads. An additional precaution may be to increase chlorine levels in the water or acidify the water to achieve the desired effect.

3.8.5. Fish, amphibians and reptiles have a highly variable species tolerance of acidity, chlorine and other chemicals. Therefore, provisions should be made to adapt the water supply of aquariums and viviers to the needs and tolerances of individual species.

3.9. Litigation

Litters should be dry, absorbent, dust-free, non-toxic, free of any infection or vermin agent or any other form of contamination. In particular, the use of sawdust or litter materials derived from chemically treated wood should be avoided. Some industrial by-products or wastes (such as shredded paper) may also be used.

3.10. Exercise and handling

3.10.1. Every opportunity should be taken to allow the animals to exercise.

3.10.2. The behaviour of the animal during a procedure depends very much on its trust in man, confidence that must be developed. The wild or wandering animal will probably never be the ideal animal for experiments. This is not the case with the domestic animal born and raised in contact with the man. Trust once established, however, should be preserved. It is therefore recommended that frequent contact be maintained so that animals become familiar with the presence and activity of humans. If so, we would have to spend some time talking to animals, dealing with them and cleaning them up. Staff should be benevolent, gentle and firm when dealing with animals.

3.11. Cleaning

3.11.1. The quality of an animal facility depends very much on its good hygiene. Clear instructions should be given for the renewal of litter, in cages and pens.

3.11.2. Adequate rules should be established for cleaning, washing, decontamination and, if necessary, the sterilization of cages and accessories, baby bottles and the rest of the equipment. It would also be appropriate to maintain a high level of cleanliness and order in the premises reserved for animals as well as in the washing and storage facilities.

3.11.3. Regular cleaning and replacement, where appropriate, of materials covering the soil in cages, enclosures and outdoor enclosures should be used to prevent them from becoming a source of infection and infestation by Parasites.

3.12. Humanitarian sacrifice of animals

3.12.1. Any humanitarian method of sacrifice of animals requires knowledge which can only be acquired through appropriate training.

3.12.2. A deeply unconscious animal can be bled, but drugs that paralyze muscles before the loss of consciousness, those with the effects of curare, and electrocution without the passage of current through the brain, should not be Used without prior anesthesia.

The removal of the body should not occur before the appearance of the corpse rigidity.

(guidelines for accommodation and care of animals)

Table 1

Guidelines for Local Temperature

(animals housed in cages or interlocks)

Species or groups of species	Optimal range in ° C
New Non-Human World Primates	20-28
Mouse	20-24
Rat	20-24
Syrian Hamster	20-24
Gerbille	20-24
Cobaye	20-24
Primates of the Old Non-Human World	20-24
Quail	20-24
Rabbit	15-21
Chat	15-21
Chien	15-21
Furet	15-21
Poultry	15-21
Pigeon	15-21
Pork	10-24
Goat	10-24
Sheep	10-24
Bovine	10-24
Horse	10-24

Note: In special cases, for example, when animals are very young or have no hairs, warmer accommodation temperatures than indicated may be required.

Table 2

Guidelines for Local Quarantine Periods

Keynote note: For imported animals, all quarantine periods should be based on the Parties' national regulations. For local quarantine periods, the period should be determined in the circumstances by a competent person, normally by a veterinarian appointed by the institution.

Species	Days
Mouse	5-15
Rat	5-15
Gerbille	5-15
Cobaye	5-15
Syrian Hamster	5-15
Rabbit	20-30
Chat	20-30
Chien	20-30
Non-human Primates	40-60

Table 3

Guidelines for the Caging of Small Rodents and Rabbits

(storage and procedures)

Species	Minimum Floor Area of the Cage 2	Minimum height of the cage cm
Mouse	180	12
Rat	350	14
Syrian Hamster	180	12
Cobaye	600	18
Rabbit	1 kg	1400	30
	2 kg	2000	30
	3 kg	2500	35
	4 kg	3000	40
	5 kg	3600	40

Note: The "cage height" refers to the vertical distance between the ground of the cage and the top horizontal part of the lid or cage.

In planning procedures, the potential growth of animals should be taken into account in order to ensure adequate space in accordance with this table during all phases of the procedures.

See also diagrams 1 through 5 and 8 to 12.

Table 4

Guidelines for the Caging of Small Rodent Rodents

Species	Minimum ground surface of the cage for a mother and its range 2	Minimum height of the cage cm
Mouse	200	12
Rat	800	14
Syrian Hamster	650	12
Cobaye	1200	18
Cobaye in harems	1000 per adult	18

Note: For the definition of "cage height", see the note in Table 3.

Table 5

Guidelines for the Cenning of Reproductive Rabbits

Weight of the lapin kg	Minimum ground surface of the cage for a rabbit and its range m 2	Minimum cage height Cm	Minimum nest area m 2
1	0.30	30	0.10
2	0.35	30	0.10
3	0.40	35	0.12
4	0.45	40	0.12
5	0.50	40	0.14

Note: For the definition of "cage height", see the note in Table 3.

The minimum ground surface of the cage for a rabbit and its range includes the ground surface of the nest box.

See also diagram 6.

Table 6

Guidelines for the accommodation of cats

(procedures and reproduction)

Cat Weight kg	Minimum floor area of the cage by cat m 2	Minimum height of the cage cm	Minimum ground surface of the cage by cat and range m 2	Minimum soil surface of the enclosure by cat and range m 2
0.5-1	0.2	50	-	-
1-3	0.3	50	0.58	2
3-4	0.4	50	0.58	2
4-5	0.6	50	0.58	2

Note: The accommodation of cats in cages should be strictly limited. Confined cats should be able to exercise at least once a day when this does not interfere with procedures. Cat pens should always be equipped with excreta trays, a rest area and objects to climb and claw.

"Cage height" means the vertical distance between the highest point of the ground of the cage and the lowest point of the top of the cage.

For the calculation of the minimum soil surface, the surface of the rest trays may be included. The minimum floor space for a cat and its range includes the 0.18 m 2 area of the kittens box.

See also diagram 7.

Table 7

Guidelines for the accommodation of dog in cages

(procedures)

Height of the dog with shoulder height	Minimum ground surface of the cage per dog m 2	Minimum height of the cage cm
30	0.75	60
40	1.00	80
70	1.75	140

Note: Dogs should not be stored in cages for longer than is absolutely necessary for the purposes of the procedure. Cage dogs should be able to exercise at least once a day, unless this is inconsistent with the purpose of the procedure. A time limit should be set beyond which an animal should not be confined without daily exercise. Exercise surfaces should be large enough to allow animals to move freely. Grilled soil should be used in dog cages only if required by the procedure.

In view of the large differences in size and the limited relationship between the size and weight of the different breeds of dogs, the height of the cage should be fixed according to the height of the body of each animal measured at the shoulders. As a general rule, the minimum height of the cage should be twice its height measured at the shoulders.

For the definition of "cage height", see the notes in Table 6.

Table 8

Guidelines for the accommodation of dogs in enclosures

(storage, procedures and reproduction)

Weight of the dog kg	Minimum soil surface of the enclosure by dog m 2	Adjacent surface of minimal exercise per dog
Kg	M 2	Up to 3 dogs m 2	More than 3 dogs m 2
<	6	0.5	0.5 (1, 0)	0.5 (1, 0)
6-	10	0.7	1.4 (2, 1)	1.2 (1, 9)
10-	20	1.2	1.6 (2, 8)	1.4 (2, 6)
20-	30	1.7	1.9 (3, 6)	1.6 (3, 3)
>	30	2.0	2.0 (4, 0)	1.8 (3, 8)

Note: The figures in brackets indicate the total area per dog, i.e. the ground surface of the enclosure plus the adjacent area of exercise. Dogs kept permanently in outdoor enclosures should have access to a sheltered location to protect themselves from adverse weather conditions. When dogs are housed on grilled surfaces, a full surface should be provided to sleep. Grilled soil should be used only if required by the procedure. Separations between enclosures should be made in such a way that the dogs cannot injure each other.

All pens should have an appropriate flow system.

Table 9

Guidelines for the Caging of Non-Human Primates

(storage, procedures and reproduction)

Keynote note: Given the very wide variety of sizes and characteristics of primates, it is particularly important to reconcile the size, interior equipment and size of the cages with their specific needs. The total volume of the cage is just as important for primates as the minimum ground surface. In general, the height of the cage, at least for anthropoid and other simian monkeys, should be its largest dimension. At a minimum, the cages should be high enough to allow the animals to stand. The minimum height of the cage for the brachiers should allow these animals to swing in the middle of the ceiling and without their feet touching the floor of the cage. Where appropriate, perches should be installed to allow the animals to use the upper part of the cage.

It is possible to house two primate primates in a cage. When primates cannot be accommodated in two, cages should be positioned so that primates can be seen, but, if so, it should also be possible to prevent them from seeing themselves.

Subject to these observations, the following table provides a general guideline for the caging of the most commonly used species groups (superfamilies of ceboids and cercopaecidae).

Weight of primate kg	Minimum ground surface of the cage for one or two animals m 2	Minimum height of the cage cm
<	1	0.25	60
1-	3	0.35	75
3-	5	0.50	80
5-	7	0.70	85
7-	9	0.90	90
9-	15	1.10	125
15-	25	1.50	125

Note: For the definition of "cage height", see the note in Table 6.

Table 10

Guidelines for Hog Cage

(storage and procedures)

Pork Weight kg	Minimum ground surface of the cage per pig m 2	Minimum height of the cage cm
5-15	0.35	50
15-25	0.55	60
25-40	0.80	80

Note: This table would also apply to piglets. Pigs should not be kept in cages unless absolutely necessary for the purpose of the procedure and, in this case, only for a minimum period of time.

For the definition of "cage height", see the note in Table 6.

Table 11

Guidelines for the accommodation of farm animals in enclosures

(storage and procedures in user institutions)

Species and weight kg	Minimum soil surface of the enclosure m 2	Minimum enclosure length m	Minimum height of separation between enclosure m	Minimum soil surface of the enclosure for groups m 2 /animal	Minimum height of feeder per head m
Swine
10-	30	2	1.6	0.8	0.2	0.20
30-	50	2	1.8	1.0	0.3	0.25
50-	100	3	2.1	1.2	0.8	0.30
100-	150	5	2.5	1.4	1.2	0.35
>	150	5	2.5	1.4	2.5	0.40
Sheep
<	70	1.4	1.8	1.2	0.7	0.35
Goats
<	70	1.6	1.8	2.0	0.8	0.35
Cattle
<	60	2.0	1.1	1.0	0.8	0.30
60-	100	2.2	1.8	1.0	1.0	0.30
100-	150	2.4	1.8	1.0	1.2	0.35
150-	200	2.5	2.0	1.2	1.4	0.40
200-	400	2.6	2.2	1.4	1.6	0.55
>	400	2.8	2.2	1.4	1.8	0.65
Adult Horses	13.5	4.5	1.8		-

Table 12

Guidelines for the accommodation of farm animals in stalls

(storage and procedures in user institutions)

Species and weight kg	Minimum stall m surface 2	Minimum Length of the m stall	Minimum height of separation between the m stalls
Swine
100-	150	1.2	2.0	0.9
>	150	2.5	2.5	1.4
Sheep
<	70	0.7	1.0	0.9
Goats
<	70	0.8	1.0	0.9
Cattle
60-	100	0.6	1.0	0.9
100-	150	0.9	1.4	0.9
150-	200	1.2	1.6	1.4
200-	350	1.8	1.8	1.4
350-	500	2.1	1.9	1.4
>	500	2.6	2.2	1.4
Adult Horses	4.0	2.5	1.6

Note: The stalls should be broad enough to allow the animals to grow comfortably.

Table 13

Guidelines for Bird Cenning

(storage and procedures in user institutions)

Species and weight g	Minimum surface per bird cm 2	Minimum surface for 2 birds cm 2	Minimum surface for 3 or more birds 2 /Bird	Minimum height of the cage cm	Minimum feeder length per bird cm
Chickens
100-300	250	200	150	25	3
300-600	500	400	300	35	7
600-1200	1000	600	450	45	10
1200-1800	1200	700	550	45	12
1800-2400	1400	850	650	45	12
(Adult Male)
> 2400	1800	1200	1000	60	15
Sizes 120-140	350	250	200	15	4

Note: "Surface" means the product of the length and width of the cage measured from the inside and horizontally, NOT the product of the length and width of the ground of the cage.

For the definition of "cage height", see the note in Table 6.

The openings of mesh in grilled soils should not exceed 10 x 10 mm for chicks and 25 x 25 mm for young birds and adults. The diameter of the wire should be at least 2 mm. Soil tilt should not exceed 14 % (8 °). Watering should be the same length as the feeders. When tetinal troughs or cups are used, each bird should have access to two tetinal troughs or two cups. The cages should be equipped with perches and allow birds in separate cages to see themselves.

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Under Art. 27 and 28 of the Convention, each Party shall compile statistical data relating to certain aspects of the procedures referred to in the Convention, and shall communicate such information to the Secretary General of the Council of Europe, who shall publish them.

It is up to each Party to choose the method used to collect the data, and there is, of course, no objection to the collection of supplementary statistical data for national needs. In order to facilitate the task of the Secretary General, however, the data provided must be comparable and correspond to the attached tables. The data are collected by calendar year.

The animals to be counted are those which are intended to be used in a manner likely to cause them lasting damage, pain, suffering or anguish (see art. 1.2.c of the Convention). Counting occurs when animals are used in a procedure. Each animal is counted only once in the same table. Animals which are not subject to procedures of the type defined in Art. 1.2.c shall not be counted for the purposes of collating statistical information under this Convention.

Because of the very nature of biological research, it is inevitable that there should be cases where it is difficult to determine in which column of a table an animal that is used in a procedure should be entered. There is no good or bad way to solve the problem; it is a matter of personal choice. Subject to the directives that the competent authorities may give, it is for the scientist to determine under what heading the animal should be included.

However, it is essential to ensure that no animals are counted twice in the same table.

Table 1

Number and kinds of animals used in procedures

In this table, the total number of animals used in procedures is mentioned, this total being broken down by type or classes of animals.

Table 2

Number of animals used in procedures for selected purposes

The purpose of this table is to show the number of animals used in the following main areas: basic research, development of new products, safety tests, disease diagnosis, education and training. In column 1, the word "medical" includes veterinary medicine.

Table 3

Number of animals used in procedures for selected purposes for the protection of humans, animals and their environment through toxicology tests or other safety tests

The purpose of this table is to provide a more detailed presentation of the procedures for the general protection of humans, animals and the environment, excluding medical purposes. Column 6 includes harmful radiation.

Table 4

Number of animals used in procedures for diseases or disorders

The purpose of this table is to indicate the number of animals used for medical purposes, including veterinary medicine, with a special reference to three areas of human disease that are of particular concern to the public.

Table 5

Number of animals used in procedures required by legislation

The column "Party concerned only" is satisfied only where the procedure is required by the law of the Party in which the procedure is carried out, including the international obligations to which that Party is subject (e.g. As a Party to the Convention on the Development of a European Pharmacopoeia ¹ Or as a Member State of the European Communities).

The column "Other Parties Only" is completed if the procedure is specifically designed to meet the requirements of countries other than the Party, including trade and convention requirements, to which it is not a party.

The "Both" section is used when the procedure is intended to satisfy the requirements of both groups; in this case, no mention is made in the other two columns.

Table 1

Number and kinds of animals used in proceedings in ... (year) in ... (Part)

	Mouse (Mus musculus)
	Rats (Rattus norvegicus)
	Cobayes (Cavia porcellus)
	Other rodents (altri Rodentia)
	Rabbits (Oryctolagus cuniculus)
	Anthropoid Singes (Hominoidea)
	Other simians (Cercopithecoidea e Ceboidea)
	Prosimians (Prosimia)
	Dogs (Canis Familiaris)
	Chats (Felis Catus)
	Other carnivores (altri Carnivora)
	Horses, donkeys and crosses (Equidae)
	Swine (Sus)
	Caprins and sheep (Capra e Ovis)
	Cattle (Bos)
	Other mammals (altri Mammalia)
	Birds (Aves)
	Reptiles (Reptilia)
	Amphibians (Amphibia)
	Fish (Pisces)
	Total

Table 2

Number of animals used in procedures for selected purposes in ... (year) in ... (Part)

	All species	Selected species
		Rodents and rabbits	Dogs and cats	Primates
1	Biological (including medical) studies of a fundamental nature
2	Discovery, development and quality control (including safety testing) of human and veterinary medicine products or devices
3	Diagnosis of diseases
4	Protection of humans, animals and the environment through toxicology tests or other safety tests
5	Education and training

Table 3

Number of animals used in procedures for selected purposes for the protection of humans, animals and the environment through toxicology tests or safety tests carried out in ... (year) in ... (Part)

Detailed classification of item 4 of Table 2	All species	Selected species
		Rodents and rabbits	Dogs and cats	Primates
1	Substances used or intended for use primarily in agriculture
2	Substances used or intended for use primarily in industry
3	Substances used or intended for use primarily as cosmetics or personal hygiene products
4	Substances used or intended for use primarily as cosmetics or personal hygiene products
5	Substances used or intended for use as food additives for the use of human consumption
6	Actual Potential Risks of Contaminants in the General Environment

Table 4

Number of animals used in procedures for diseases or disorders in ... (year) in ... (Part)

	All species	Selected species
		Rodents and rabbits	Dogs and cats	Primates
1	Cancer (excluding carcinogens)
2	Cardiovascular Disease
3	Nervous and mental disorders
4	Other human and animal diseases

Note: When a procedure relates to cancer under all headings from 2 to 4, the cancer classification should preferably be applied.

Table 5

Number of animals used in procedures required by the legislation in ... (year) in ... (Part)

	All species	Selected species
		Rodents and rabbits	Dogs and cats	Primates
Party concerned only
Other Parties only
Both

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