Key Benefits:
The Minister of Labour, Employment and Health and the Minister of Higher Education and Research,
Considering the education code, including article L. 633-2;
Vu le Public Health Codeincluding articles R. 6152-1 to R. 6152-4;
Vu le Decree No. 2007-704 of 4 May 2007 relating to the organization and operation of the National Centre for the Management of Hospital Practitioners and Management Personnel of the Hospital Public Service and amending the Public Health Code (regulatory provisions);
Vu le Decree No. 2012-172 of 3 February 2012 relating to the third specialized cycle of pharmaceutical studies;
Vu le Decree No. 2012-173 of 3 February 2012 special provisions relating to the third specialized cycle of pharmaceutical studies;
In view of the Order of 29 June 1992 setting out the list of sections, sub-sections and options as well as the number of members of each section and sub-section of the groups of the National Council of Universities for medical, odontological and pharmaceutical disciplines;
In view of the decision of September 25, 2008 on scientific advice and procedures for the management and organization of the postgraduate medical, pharmaceutical and odontological examinations by the National Centre for the Management of Hospital Practitioners and Management Personnel of the Hospital Public Service;
In view of the decree of October 31, 2008 regulating the specialized pharmacy diplomas;
In view of the decision of 31 October 2008 setting out the list of specialized pharmacy diplomas;
Considering the opinion of the National Council for Higher Education and Research of 19 March 2012,
Stop:
It is organized annually a national pharmacy internship competition.
In application of theArticle 6 of Decree No. 2012-172, an order of the Director General of the National Centre for the Management of Hospital Practitioners and Management Personnel of the Public Hospitaller Service sets, each year, the schedule of the examinations of the pharmacy boarding competition.
The program of the pharmacy internship contest is annexed to this Order.
The trials of the pharmacy boarding contest are written and anonymous. Their nature, duration and rating are as follows:
A. ― First test (duration: 1 h 30):
General knowledge questions: 60 multiple-choice questions (MCQs).
Rating on 120 points.
B. ∙ Second (duration: 2 hours):
Five application exercises (digital or non-digital), each noted on 40 points.
Rating on 200 points.
C. ― Third test (duration: 3 hours):
Five therapeutic and biological records, each of 60 points, including issues related to the elements of these files and, where applicable:
- general knowledge editorial issues;
– questions about the usual biological values scored on 5 points per file.
Rating on 300 points.
The correction of the multi-choice question test (MCQ) is automated.
For single-choice questions, the candidate obtains the maximum of the rating if the answer is in accordance with the grid, the answer is zero if it differs. The correction of multiple-choice questions takes into account the concept of coherence of the response elements in the following principle: the totality of the note for five consistency, half of the note for four consistency, fifth of the note for three coherence, and other options not giving any point.
Each application exercise and each therapeutic and biological file is subject to a double independent and anonymous correction. The note is the arithmetic mean of both notes. Where, for the same exercise or record, the rating gap between two correctors is equal to or greater than 5% of the maximum rating for the fiscal year or file, pursuant to section 3 above, a third correction shall be made. In this case, the resulting note is retained.
The jury is appointed by the Director General of the National Centre for the Management of Hospital Practitioners and Management Personnel of the Hospital Public Service.
It is composed of a president appointed on the proposal of the president of the scientific council in pharmacy and thirty incumbent members from the pharmaceutical disciplines of the National Council of Universities for medical, odontological and pharmaceutical disciplines referred to in article 2-2 of the above-mentioned decree of 29 June 1992, drawn by lot and distributed as follows:
twenty professors in pharmaceutical disciplines, including at least five in the body of university professors-patients in pharmaceutical disciplines;
– ten lecturers in pharmaceutical disciplines, including at least three in the body of lecturers from universities-patients in pharmaceutical disciplines.
After drawing the lot of the members holding the jury, in the same conditions, the drawing of the lot of a first and a second alternate of each member.
The Director General of the National Centre for the Management of Hospital Practitioners and Management Personnel of the Hospitaller Public Service or his representative shall draw the fate of the members of the jury referred to in section 6 above.
Participation in the jury's work of the boarding school competition is mandatory.
Persons who have a direct or collateral online relationship, up to the second degree included, with one of the candidates must be challenged as members, holders or alternates, of the jury.
If a member ceases to sit after the start of the corrections, he or she cannot regain his or her place or be replaced.
The correction of the trials is carried out under the responsibility of the president of the jury.
The ex aequo are departed according to the best score obtained in the third test. If this method proves insufficient, it is taken into account the best grade in the second test. If ex aequo remain, they are left for the benefit of the older.
The decision to use the reserve exercise or therapeutic record in the event of a serious material error in the wording of the tests or in the event of a serious incident belongs to the jury president.
When a decision of the jury requires a voting procedure, in the event of equal sharing of votes, the vote of the jury chair is preponderant.
The president of the jury distributes the task of the members of the jury.
Two lists of rankings are decided by the jury in order of merit: a list of senior candidates and a list of complementary candidates established within the limit of the number of positions being contested.
The Director General of the National Centre for the Management of Hospital Practitioners and Management Staff of the Hospital Public Service shall notify each candidate of the results obtained in the pharmacy internship competition and publish the lists on the Centre's website: www.cng.sante.fr.
Applicants submit to the National Centre for the Management of Hospital Practitioners and Hospitaller Public Service Management a registration file composed of:
1. The completed registration form legibly and completely.
2. A photocopy of the valid identity card or passport on the date of filing of the file.
3. The second-cycle diploma of pharmaceutical studies or a certificate from the original training and research unit of the candidate stating that the individual has validated the fourth year of pharmaceutical studies.
4. Where applicable, the documents justifying an exemption.
All of the above-mentioned documents must be sent by the candidates no later than the closing date of the registrations under penalty of inadmissibility.
Nomination conditions are appreciated on the closing date of registration.
ACCESS OF THE RESOLUTIONAL PHARMACIES OF THE MEMBERS OF THE EUROPEAN UNION, TO BE A PART OF THE ACCORD ON EUROPEAN ECONOMIC SPACE, THE PRINCIPLE OF ANDORITY OR THE CONFERENCE SWITZEN TO THE TRAINING OF THE THIRD IMPLEMENTATION
The National Centre for the Management of Hospital Practitioners and Management Personnel of the Hospital Public Service organizes the European-based internship competition referred to in Chapter I of the above-mentioned Decree No. 2012-173.
It takes place in the same test centers as the national pharmacy boarding competition.
The provisions of Chapter II of Title I of this Decree relating to the programme and conduct of the examination and those of Chapter III relating to the composition and functioning of the jury shall apply to the candidates referred to in this title.
Candidates from the European boarding competition address the National Centre for the Management of Hospital Practitioners and Hospitaller Public Service Management a registration file composed of the following:
1. The completed registration form legibly and completely.
2. A photocopy of an official identity document indicating the nationality of the candidate, which is valid on the date of filing of the file.
3. A copy of the diploma, certificate or title allowing the exercise of the profession in one of the Member States of the European Union, another State Party to the agreement on the European Economic Area, the Principality of Andorra or the Swiss Confederation. It shall be accompanied, if any, by the certificate of professional competence issued by the competent authorities of that State and giving access to the profession of pharmacist.
4. Any document issued by the competent authorities certifying that the candidate has exercised for at least three years the professional activity of a pharmacist in one of the States mentioned in paragraph 3 of this article.
All of the above-mentioned documents must be sent by the candidates no later than the closing date of the registrations under penalty of inadmissibility.
Nomination conditions are appreciated on the closing date of registration.
The supporting documents must be written in the French language, or translated by a translator accredited to the French courts or authorized to intervene with the judicial or administrative authorities of a Member State of the European Union or another State Party to the agreement on the European Economic Area.
ACCESS TO THE SPECIALIZED TRAINING OF THE THIRD SPECIALIZED CYCLE OF THE PHARMACEUTICAL STUDY OF THE PHARMACIANS OTHER THANKS OF THE EUROPEAN UNION OF ANY PART OF THE EUROPEAN AGREEMENT
The National Centre for the Management of Hospital Practitioners and Management Personnel of the Hospital Public Service organizes the foreign pharmacy boarding competition referred to in chapter IV of the above-mentioned Decree No. 2012-173.
It takes place in the same test centers as the national pharmacy boarding competition.
The provisions of Chapter II of Title I of this Decree relating to the programme and conduct of the examination and those of Chapter III relating to the composition and functioning of the jury shall apply to the candidates referred to in this title.
In application of theArticle 15 of Decree No. 2012-173, applicants from the foreign boarding competition send to the National Centre for the Management of Hospital Practitioners and Management Personnel of the Hospital Public Service a registration file composed of the following documents:
1. The completed registration form legibly and completely.
2. A photocopy of an official identity document indicating the nationality of the candidate, which is valid on the date of filing of the file.
3. A copy of the degree, certificate or title allowing the practice of the pharmacy in the country of obtaining or origin of the candidate.
4. A statement on the honour attesting that the candidate is not a national of one of the Member States of the European Union or one of the States parties to the agreement on the European Economic Area, the Principality of Andorra or the Swiss Confederation.
All of the above-mentioned documents must be sent by the candidates no later than the closing date of the registrations under penalty of inadmissibility.
Nomination conditions are appreciated on the closing date of registration.
The supporting documents must be written in the French language, or translated by a translator accredited to the French courts or authorized to intervene with the judicial or administrative authorities of a Member State of the European Union or another State Party to the agreement on the European Economic Area.
Following the publication of the results of the boarding competitions by the National Centre for the Management of Hospital Practitioners and Management of the Hospital Public Service, a national and computerized post selection procedure is organized as follows.
The National Management Centre collects the vows of assignment by inter-region, speciality and hospital and university-based linking that, in preferential order, candidates placed on the main and complementary lists.
Any candidate who has not expressed his or her wishes or has not issued a sufficient number of wishes to affect him or her loses the benefit of his or her ranking.
These assignments are published in the Official Journal of the French Republic by order of the Director General of the National Centre for the Management of Hospital Practitioners and Management Personnel of the Hospital Public Service.
In application of theArticle 16 of Decree No. 2012-173 and in addition to the computerized procedure provided for in the first paragraph of Article 20 of this Order, candidates from the boarding competition abroad shall also communicate their choice of position in writing to the National Centre for the Management of Hospital Practitioners and Management Personnel of the Hospital Public Service.
The National Centre for the Management of Hospital Practitioners and Management Personnel of the Hospital Public Service shall notify each candidate of the boarding competition on a foreign basis.
The provisions of this Order apply to open pharmacy boarding competitions for the 2012-13 academic year.
The decision of 24 August 2009 concerning the organization of the contests and determination of the interregions of the boarding of pharmacy and the organization of the procedure of choice of post, the decree of 15 March 2010 concerning the special examinations provided for the access of pharmacists nationals of a Member State of the European Union or of another State party to the agreement on the European Economic Area, the Principality of Andorra or the Swiss Confederation
The Director General of the Care Offer and the Director General for Higher Education and Vocational Integration are responsible, each with respect to it, for the execution of this Order, which will be published in the Official Journal of the French Republic.
A N N E X E
PROGRAMME OF CONCOURS
DE L'INTERNAT EN PHARMACIE
Section I – Mathematics, Physical Sciences
(questions 1 to 18)
Principles and applications:
1. Separation methods based on extraction (solid-liquid and liquid-liquid).
2. Atomic emission and absorption spectrophotometry.
3. Spectrophotometry of UV-visible molecular absorption.
4. Molecular spectrofluorimetry.
5. Chromatographic methods: gas chromatography; liquid chromatography (excluding-diffusion, exchange of ions, sharing).
6. Electrophoretic methods including detection principles.
7. Electrochemical redox methods of analysis including detection principles: potentiometry, amperometry.
8. Osmotic pressure: osmolarity, osmolality.
9. Analysis of chiral compounds.
10. Main structural and physico-chemical properties of organic functions: alcohol, phenol, amine, thiol, aldehyde, cetone and carboxylic acid. Applications to derivate. Stereo-isomer.
11. X rays and radiation emitted by the major radioisotopes used in vivo and in vitro.
12. The ions in solution:
― acid-base balance in aqueous solution, pH, pK, buffer solutions;
– reactions and balances of complexity.
13. Protometry in non-aqueous medium.
14. Criteria for the validity of an analysis method: accuracy, accuracy, linearity, specificity, detection limits and quantification.
15. Methods using antigen antibodies reaction.
16. Descriptive statistics: estimation of population parameters, confidence interval of an average and proportion.
17. Parametric comparison tests:
Unilateral or bilateral comparison:
- two variances observed;
- an average observed at a theoretical value;
- two observed averages.
Unilateral or bilateral comparison for large samples:
a proportion observed to a theoretical proportion;
- two proportions observed.
18. Link tests:
― linear regression: estimation and confidence interval of the slope and the tip at the origin. Comparison with a theoretical value of the slope and the tip at the origin;
- linear correlation: estimation and test of correlation coefficient (r);
- test of independence chi-two.
Section II. • Life Sciences
(questions 1 to 31)
This section excludes the study of any pathology.
1. Structure, organization, dynamic and polymorphism of the human genome.
2. Setting the expression of protein-coding genes in eucaryotes.
3. Different modes of transmission of hereditary monogenic diseases.
4. Methods for identifying delegitimate mutations that cause monogenic hereditary diseases.
5. Mechanisms and consequences of the delegitimate mutations causing monogenic hereditary diseases.
6. Caryotype and constitutional chromosomal anomalies.
7. Measurement of an enzymatic activity, applications.
8. Ammoniogenesis and ureogenesis.
9. Structure, biosynthesis and catabolism of hemoglobin.
10. Structure and properties of nucleic acids, lipoproteins.
11. Control of blood glucose.
12. Metabolism of fatty acids, triglycerides, cholesterol, lipoprotein.
13. Cetogenesis.
14. Neurotransmitters: acetylcholine, gamma-aminobutyric acid, adrenaline, dopamine, noradrenaline, serotonin, glutamate.
15. Cardiovascular physiology.
16. Physiology of breathing.
17. Digestive Physiology.
18. Renal Physiology.
19. Physiology of corticorenals.
20. Physiology of thyroid.
21. Menstrual cycle and physiology of pregnancy.
22. Pain physiology.
23. Bone Physiology, regulation of calcemia and phosphatemia.
24. Physiology of myeloid lines.
25. Blood groups A, B, O, Rhesus and Kell.
26. Physiology of primary hemostasis, coagulation, fibrinolysis.
27. Structure and properties of immunoglobulins.
28. Innate immunity and inflammation.
29. A major complex of histopoly and antigen presentation.
30. Organs and cells of the immune response.
31. Comics and cellular immune responses and their regulation.
Section III. Public Health Sciences
and the environment (questions 1-16)
1. Health surveillance and vigilance: definition, objectives and organization.
2. Prevention and promotion of health.
3. Vaccine policy: development, recommendations and evaluation.
4. Drug addictive conduct: prevention and care.
5. Epidemiological methodology:
descriptive epidemiology: objectives, surveys, indicators;
etiologic epidemiology: objectives, surveys, indicators;
―evaluative epidemiology and screening.
6. Medical drugs and medical devices: definitions, statutes and socio-economic aspects at the hospital.
7. Health institutions, guardianship structures, pharmacies for internal use.
8. Patient rights.
9. Iitrogen risk. Risk nosocomial.
10. Health risks associated with physico-chemical and microbiological characteristics of water.
11. Toxicology of ethanol, methanol, ethylene-glycol and glycol ethers.
12. Toxicology of aromatic hydrocarbons (benzene, toluene, polycyclic aromatic hydrocarbons), aliphatic chlorinated solvents and dioxins.
13. Toxicology of phytosanitary products: organophosphores, carbamates.
14. Hemolytic. Hemoglobin Poisons: carbon oxide, lead, methemoglobinizing.
15. Radioelement toxicity.
16. Drug abuse: opiate, LSD, cocaine, amphetamine, cannabis.
Section IV. ― Elements of semeiology
and pathology. Biology applied to the clinic
Bacterial and viral infections (questions 1 to 11)
Physiopathological bases and major clinical signs of the most common infections; principles of biological diagnosis, treatment, prevention and monitoring of bacterial and viral infections:
1. Infections of the central nervous system.
2. Bacteremia and endocarditis.
3. Urinary infections.
4. Digestive tube infections.
5. ORL and bronchopulmonary infections.
6. Sexually transmitted infections.
7. Infections and pregnancy.
8. Hepatic viral infections.
9. Immunodepressed infections.
This includes a summary description of bacteria (morphology, cultural characters, identification, excluding biochemicals of species) and viruses (classification, structure, identification) as follows: Neisseria gonorrhoeae and Neisseria meningitidis, Staphylococcus aureus, Streptococcus pyogenes, Streptococcus agaliae,
10. Principle of sensitivity and resistance of bacteria and viruses to anti-infective agents.
11. Anti-infective resistance mechanisms.
Parasitoses and mycoses (questions 12-21)
Study of epidemiology, major clinical signs, basics of biological diagnosis, treatment, prophylaxis and follow-up to the following parasitoses and mycoses:
12. intestinal protozoosis: amibiase (entamoebose), giardiosis.
13. Urogenital trichomonosis.
14. Paludism.
15. Toxoplasmosis.
16. Leishmaniose to Leishmania infantum.
17. Helminthoses intestinal and hepatic: fasciolosis in Fasciola hepatica, bilharziosis in Schistosoma mansoni, téniasis in Taenia saginata, hydatidosis in Echinococcus granulosus, oxyurosis, anguillulosis.
18. Yeast infections (Candida albicans, Cryptococcus neoformans).
19. Infections in Aspergillus fumigatus.
20. Dermatophytes (Microsporum canis, Trichophyton rubrum, Trichophyton mentagrophytes).
21. Pneumocystose to Pneumocystis jirovecii.
This study includes a summary description of the parasites and responsible fungi, excluding the biochemical characters of the species.
Hematology and immunology (questions 22 to 38)
Etiology, main clinical signs, basics of biological diagnosis, treatment and evolution of the following conditions:
22. Carential anemia. Hemolytic anemia.
23. Polyglobulies.
24. Chronic myeloid leukemia.
25. Hemophilia. Willebrand's disease.
26. Hemoglobinopathies: drepanocytosis, thalassemia.
27. Myeloma and monoclonal dysglobulinemia of undetermined meaning.
28. Acute leukemia and myelodysplastic syndromes (excluding classifications).
29. Hyperlymphocytosis: mononuclear syndromes, chronic lymphoid leukemia, lymphomas (excluding classifications).
30. Drug cytopenia.
31. Thrombopennies.
32. Asthma and allergies.
33. Autoimmune diseases: rheumatoid arthritis and systemic lupus.
34. Congenital immune deficits.
35. Exploring inflammatory reactions.
36. Diagnosis of an elongation of Quick and/or Cephaline time with activator.
37. Biological monitoring of heparin and antivitamin treatment K.
38. Labile blood products: definition, indications, pretransfusion.
Other affections (questions 39-53)
Physiopathological bases, major clinical signs, basics of biological diagnosis, treatment and monitoring of the following conditions:
39. Diabetes of types 1 and 2.
40. Hyperlipoproteinemia.
41. Hydro-electronic balance disorders.
42. Disorders of acidobasic balance.
43. Bone metabolism disorders.
44. Cholestase, liver cytolysis, liver failure.
45. Iron metabolism disorders.
46. kidney failure, nephrotic syndrome.
47. Acute coronary accidents, heart failure.
48. Hyperuricemia.
49. Acute pancreatitis.
50. Corticosurreal malfunctions.
51. Thyroid dysfunctions.
52. Proteino-energetic malnutrition.
53. Neurological and neurodegenerative disorders: epilepsy, migraines, facial alkalis ― Alzheimer's disease, Parkinson's disease, multiple sclerosis.
Genetics (questions 54 and 55)
54. Review of a person's genetic characteristics for medical purposes.
55. Prenatal diagnosis of genetic diseases.
Section V. ― Drug Science
(questions 1-59)
Become a drug in the body:
1. Main steps: resorption, distribution, biotransformation, excretion.
2. Factors influencing the fate of active principles: physiological factors, pathological states, associated xenobiotics.
3. Bioavailability: definition, principle of study methods and factors of variation.
4. Key pharmacokinetic parameters: mechanisms and methods of action of drugs.
5. Targets of drugs, characteristics of receptor connections, methods of study.
6. Courbe effect-dose, effective dose 50, notion of therapeutic margin: general structure, international common name, structural-activity relationship, action mechanism, pharmacological properties, pharmacokinetics, indications (limited to market authorization), galenic forms, job precautions, contraindications, adverse effects and drug interactions of drugs belonging to the following classes.
7. Medicines of neurological and neurodegenerative conditions: epilepsy, migraines, facial aches, Alzheimer's disease, Parkinson's disease, multiple sclerosis.
8. Antalgic.
9. Antipsychotics.
10. Anxiolytics and sleep disorder medications.
11. Antidepressants. Normothymics.
12. Heart failure medication.
13. Anti-anguish.
14. Antihypertensors.
15. Diuretics.
16. Medicines of hemostasis disorders: anticoagulants, anti-aggregate agents, thrombolytics.
17. Vascular filling solutes.
18. Medical heart rate disorders.
19. Antiasthmatic and antiallergic.
20. Anti-inflammatory.
21. Drugs of the drop.
22. Antidiabetics: oral and insulin antidiabetics.
23. Antibacterial sulfides and associations.
24. Lactames.
25. Macrolides and related.
26. Cyclines.
27. Aminosides.
28. Glycopeptides.
29. Quinolones.
30. Antituberculosis.
31. Antiretroviral.
32. Active antivirals against hepatitis viruses, influenza viruses and herpes viruses.
33. Anti-fungal by general means.
34. intestinal and intestinal antiprotozoa.
35. Antimalarial.
36. Medicines of the gastro-duodenal ulcer.
37. Antiemetic.
38. Immunosuppressors.
39. Hematopoietic growth factors. Cytokines and antagonists.
40. Medicines of thyroid dysfunctions.
41. Normolipemians.
42. Anticancerous: classification and mechanisms of action, principles of their therapeutic use and associated treatments.
Note that the associated treatments (adjuvant therapy) are treated in other subsections of section V.
43. Osteoporosis drugs.
Toxic effects of drugs:
44. Methods for assessing the toxicity of a drug.
45. Systemic toxicity: mechanisms and manifestations of hematological, liver, kidney, cardiovascular or lung action.
46. Psychotropic toxicity: lithium, benzodiazepines, carbamates, neuroleptics, antidepressants.
47. Toxicology of antalgics: salicylés, paracetamol and morphinomimetics.
48. Cardiotoxic drugs: digoxin, chloroquine.
49. General principles of poisoning treatment methods. Antidotes.
Forming and enhancing the drug:
50. Sterilization and aseptic conditioning of medications.
51. Conventional release forms for oral and parenteral channels.
52. Modified forms of release and/or distribution for oral and parenteral channels.
53. Parental nutrition preparations.
54. Shapes for nasal and lung paths.
55. Shapes intended for cutaneous pathways (including transdermal) and ocular.
Principles of production and use of:
56. Plasma-derived drugs: albumin, hemostasis and immunoglobulins.
57. Vaccines: hepatitis B, ROR (rubéole-oreillons-rougeole), tetanus, flu.
58. Monoclonal antibodies.
59. Hematopoietic stem cells.
The QCM and application exercises are for the entire program defined in sections I to V.
Therapeutic and biological records that may include general knowledge editorial issues (QRCG) cover sections II, III, IV and V.
Biological values that can be requested in therapeutic and biological records are only adults. These are those published by the Scientific Council in pharmacy.
Done on 12 April 2012.
The Minister of Labour,
employment and health,
For the Minister and by delegation:
Director General
offer of care,
F.-X. Selleret
Minister of Higher Education
and research,
For the Minister and by delegation:
Director General
for higher education
and professional integration,
J.-L. Mucchielli
