4717.7860 Health Risk Limits Table


Published: 2015

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4717.7860 HEALTH RISK LIMITS TABLE.


§
Subpart 1.

Generally.

This table lists the health risk limits derived from methods specified in parts 4717.7830, 4717.7840, and 4717.7850. For each chemical, this table specifies:

§
A.

the chemical name;


§
B.

the CAS number;


§
C.

the year the HRL was adopted;


§
D.

the volatility classification;


§
E.

any noncancer HRL;


§
F.

any cancer HRL;


§
G.

the RfD and RSC used in the derivation of any noncancer HRL;


§
H.

the slope factor and any ADAF or AFlifetime used in the derivation of any cancer HRL;


§
I.

the intake rate used in the derivation of any noncancer or cancer HRL; and


§
J.

the health endpoints.



§
Subp. 2.

Explanation of table in this part.


§
A.

"-" symbol means not relevant.


§
B.

"NA" means not applicable.


§
C.

"ND" means not derived due to absence or paucity of toxicity information.


§
D.

"None" means not applicable for inclusion in the health risk index.


§
E.

The following explanations in subitems (1) to (3) apply where noted:

§
(1)

The acute HRL value is less than the calculated HRL. To be protective of acute exposures, the HRL is set equal to the acute HRL value.


§
(2)

The short-term HRL value is less than the calculated HRL. To be protective of short-term exposures, the HRL is set equal to the short-term HRL value.


§
(3)

The subchronic HRL value is less than the calculated HRL. To be protective of subchronic exposures, the HRL is set equal to the subchronic HRL value.




§
Subp. 3.

Acetochlor.



CAS number: 34256-82-1


Year Adopted: 2009


Volatility: Nonvolatile



Acute


Short-term


Subchronic


Chronic


Cancer



HRL (µg/L)

40
40
40 (2)
9
NA


RfD (mg/kg-day)

0.021
0.021
(2)
0.002
--


RSC

0.5
0.5
(2)
0.2
--


SF (per mg/kg-day)

--
--
--
--
--


ADAF or AFlifetime

--
--
--
--
--


Intake Rate (L/kg-day)

0.289
0.289
(2)
0.043
--


Endpoints

developmental
developmental
developmental
hepatic (liver) system, male reproductive system, nervous system, renal (kidney) system, respiratory system
--



§
Subp. 3a.

Acetochlor ESA.



CAS number: 187022-11-3


Year Adopted: 2011


Volatility: Nonvolatile



Acute


Short-term


Subchronic


Chronic


Cancer



HRL (µg/L)

ND
600
600
300
NA


RfD (mg/kg-day)

--
0.37
0.23
0.075
--


RSC

--
0.5
0.2
0.2
--


SF (per mg/kg-day)

--
--
--
--
--


ADAF or AFlifetime

--
--
--
--
--


Intake Rate (L/kg-day)

--
0.289
0.077
0.043
--


Endpoints

--
thyroid (E)
thyroid (E)
thyroid (E)
--



§
Subp. 3b.

Acetochlor OXA.



CAS number: 184992-44-4


Year Adopted: 2011


Volatility: Nonvolatile



Acute


Short-term


Subchronic


Chronic


Cancer



HRL (µg/L)

ND
200
200
100
NA


RfD (mg/kg-day)

--
0.12
0.077
0.026
--


RSC

--
0.5
0.2
0.2
--


SF (per mg/kg-day)

--
--
--
--
--


ADAF or AFlifetime

--
--
--
--
--


Intake Rate (L/kg-day)

--
0.289
0.077
0.043
--


Endpoints

--
thyroid (E)
thyroid (E)
thyroid (E)
--



§
Subp. 3c.

Acetone.



CAS number: 67-64-1


Year Adopted: 2011


Volatility: Moderate



Acute


Short-term


Subchronic


Chronic


Cancer



HRL (µg/L)

ND
9,000
8,000
4,000
NA


RfD (mg/kg-day)

--
5.0
3.0
0.90
--


RSC

--
0.5
0.2
0.2
--


SF (per mg/kg-day)

--
--
--
--
--


ADAF or AFlifetime

--
--
--
--
--


Intake Rate (L/kg-day)

--
0.289
0.077
0.043
--


Endpoints

--
renal (kidney) system
renal (kidney) system, hematological (blood) system
renal (kidney) system, hematological (blood) system
--



§
Subp. 3d.

6-Acetyl-1,1,2,4,4,7-hexamethyltetraline (AHTN).



CAS number: 21145-77-7 or 1506-02-1


Year Adopted: 2013


Volatility: Moderate



Acute


Short-term


Subchronic


Chronic


Cancer



HRL (µg/L)

ND
100
30
20
NA


RfD (mg/kg-day)

--
0.070
0.011
0.0037
--


RSC

--
0.5
0.2
0.2
--


SF (per mg/kg-day)

--
--
--
--
--


ADAF or AFlifetime

--
--
--
--
--


Intake Rate (L/kg-day)

--
0.289
0.077
0.043
--


Endpoints

--
hepatic (liver) system
hepatic (liver) system
hepatic (liver) system
--



§
Subp. 4.

Alachlor.



CAS number: 15972-60-8


Year Adopted: 2009


Volatility: Nonvolatile



Acute


Short-term


Subchronic


Chronic


Cancer



HRL (µg/L)

ND
200
30
5
NA


RfD (mg/kg-day)

--
0.1
0.01
0.001
--


RSC

--
0.5
0.2
0.2
--


SF (per mg/kg-day)

--
--
--
--
--


ADAF or AFlifetime

--
--
--
--
--


Intake Rate (L/kg-day)

--
0.289
0.077
0.043
--


Endpoints

--
renal (kidney) system
hepatic (liver) system, hematological (blood) system
hepatic (liver) system, hematological (blood) system
--



§
Subp. 5.

Atrazine.



CAS number: 1912-24-9


Year Adopted: 2009


Volatility: Nonvolatile


MCL-based HRL: 3 µg/L



§
Subp. 6.

Benzene.



CAS number: 71-43-2


Year Adopted: 2009


Volatility: High



Acute


Short-term


Subchronic


Chronic


Cancer



HRL (µg/L)

10
10
3
3 (3)
2


RfD (mg/kg-day)

0.015
0.014
0.0013
(3)
--


RSC

0.2
0.2
0.2
(3)
--


SF (per mg/kg-day)

--
--
--
--
0.055


ADAF

--
--
--
--
10 (ADAF